156-816 Certification Brain Dumps Source : Check Point Certified Managed Security Expert Plus VSX NGX
Test Code : 156-816
Test title : Check Point Certified Managed Security Expert Plus VSX NGX
Vendor title : CheckPoint
: 106 actual Test Questions/Answers
(GlobeNewswire) - check ingredient application technologies Ltd. (NASDAQ:CHKP) these days introduced check aspect SandBlast cellular got Miercoms licensed comfy Award within the first independent, mobile danger defense check these days carried out by means of the impartial testing company. here's Miercoms highest award for success in competitive, palms-on trying out. The results spotlight SandBlast Mobiles management and excellence in protection and usefulness over other cellular risk protection competitors.
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Malicious malware and applications which provide hackers the capacity to control and entry as a mock user
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mobile gadget vulnerabilities comparable to root-purchasable smartphones and old-fashioned firmware
Highlights of examine point SandBlast Mobiles consequences encompass:
Detected and blocked 100 percent of malicious purposes and community attacks
Delivered 33 percent more suitable insurance plot towards network assaults than the trade regular most notably against MitM authentication-primarily based threats
Detected 20 p.c more Android and iOS machine vulnerabilities than the regular MTD solution
Mitigated every bit of device vulnerabilities, in spite of working gadget
"verify point SandBlast cell performed the most excellent general in the Miercom trade assessment of mobile risk defense (MTD) items, observed Rob Smithers, Miercom CEO. SandBlast cellular undeniably proved its effectiveness in the business in opposition t threats borne via business cellular devices and BYOD vector threats."
We noticed in a coincident survey carried out by way of Dimensional analysis that ninety four percent of cyber protection experts expect the frequency of mobile assaults to raise, observed Michael Shaulov, head of mobile and cloud items at examine point. The Miercom industry assessment demonstrates that SandBlast cellular detects and blocks essentially the most subtle hacks improved than every bit of their opponents, and provides the protection that every mobile business requires.
For more information, or to download a complimentary reproduction of the Miercom record of verify elements SandBlast Mobiles spy at various consequences, consult with: http://pages.checkpoint.com/miercom-record-on-sandblast-cellular.html
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About verify point utility technologies Ltd.check aspect application applied sciences Ltd. (www.checkpoint.com) is the greatest network cyber security seller globally, proposing business-main options and preserving customers from cyberattacks with an unmatched capture expense of malware and different sorts of threats. verify factor offers an entire protection structure defending corporations from networks to mobile devices besides the most finished and intuitive security management. verify ingredient protects over one hundred,000 groups of every bit of sizes.
(c) 2017 Kabulpress.org. every bit of rights reserved. supplied through SyndiGate Media Inc. (Syndigate.data)., source seat East & North African Newspapers
On Saturday, June 2nd from 10am - 1pm, the Lake County Sheriff's office along with the geographical region fireplace branch will offer a vehicle Seat safety determine on the countryside hearth branch, Station 1, 801 S. Midlothian in Mundelein.
The examine point is for every bit of fogeys, grandparents and caretakers who exigency assist installation their newborn seat or would really dote an authorized technician to check their installed seat for commandeer healthy. child restraint setting up can exist difficult because of so numerous makes and models of cars and seats. Attendees are asked to deliver their vehicle manuals and newborn seat manuals, if accessible, to the adventure. The examine is offered at no cost.
"We encourage residents to choose skills of this checkpoint", stated Sheriff label Curran. "Our babies are their future, let's offer protection to them as choicest they will," he brought.
Bauchi — A policeman has been killed and three others injured with the aid of one of a number of soldiers manning a CheckPoint in Bauchi State.
The Bauchi status Police Command spokesperson, DSP Haruna Mohammed, renowned in an announcement the day before today that 18 cops who were traveling in a bus from Taraba status Command to Kaduna for a promoting direction were stopped at a military determine point in Panshanu Village of Toro LGA of Bauchi status and their car became searched and allowed to proceed, but that one unidentified soldier connected to 33 Artillery Brigade, Bauchi, shot on the bus from the rear glass and escaped.
"because of this, one F/N 500331 laptop Bwala Mohamned died immediate while three others sustained a lot of levels of injuries," the police pro stated, including that the scene become visited by means of a police patrol group led with the aid of the DPO of Toro division and victims rushed to Toro familiar sanatorium for remedy and the corpse of the deceased police officer became deposited at the mortuary for submit-mortem examination after being licensed lifeless by using a medical medical professional.
He mentioned one AK 47 rifle abandoned by way of the soldier with 31 rounds of live ammunition become recovered and the case become beneath investigation.
On his own, the spokesperson of 33 Artillery Brigade of the Nigerian military Bauchi, major Joseph Adekunle Afolashade, observed in a sever observation that troops deployed at Panshanu assess-point along Bauchi-Jos highway opened hearth on a bus that drove dangerously in the course of the CheckPoint and refused to cease when flagged down.
He cited that the troopers acted on suspicion that the bus might exist conveying terrorists or armed criminal features, but that preliminary investigation had established the id of the occupants to exist policemen who had been in mufti.
"unluckily, one person died and 3 others sustained accidents within the manner," the 33 Artillery Brigade spokesperson mentioned.
156-816 Certification Brain Dumps Source : Check Point Certified Managed Security Expert Plus VSX NGX
Test Code : 156-816
Test title : Check Point Certified Managed Security Expert Plus VSX NGX
Vendor title : CheckPoint
: 106 actual Test Questions/Answers
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Nestler EJ, Gould E, Manji H, Buncan M, Duman RS, Greshenfeld HK et al. Preclinical models: repute of basic research in depression. Biol Psychiatry 2002; fifty two: 503–528.
American Psychiatric association. Diagnostic and Statistical steer of mental problems, 4th edn. American Psychiatric affiliation: Washington, DC, 1994.
Heninger GR, Charney DS, Sternberg DE. Serotonergic duty in melancholy. Prolactin response to intravenous tryptophan in depressed patients and felicitous topics. Arch Gen Psychiatry 1984; 41: 398–402.
Heninger GR. Indoleamines: the position of serotonin in medical disorders. In: prime FE, Kupfer DJ (eds). Psychopharmacology: The Fourth era of development. Raven Press, Ltd.: long island, 1995, pp 471–482.
Naughton M, Mulrooney JB, Leonard BE. A assessment of the position of serotonin receptors in psychiatric issues. Hum Psychopharmacol 2000; 15: 397–415.
Stanford SC. 5-Hydroxytryptamine. In: Webster RA (ed). Neurotransmitters, drugs and intellect function. John Wiley & Sons Ltd: manhattan, 2001, pp 187–209.
Leonard BE. Fundamentals of Psychopharmacology, 2nd edn. Wiley & Sons: manhattan, 1997.
Jacobs BL, Fornal CA. Serotonin and habits. In: prime FE, Kupfer DJ (eds). Psychopharmacology: The Fourth generation of growth. Raven Press, Ltd.: ny, 1995, pp 461–469.
Coppen A, Eccleston E, Craft I, Bye P. Letter: complete and free plasma-tryptophan attention and oral contraception. Lancet 1973; 2: 1498.
Cowen PJ, Parry-Billings M, Newsholme EA. decreased plasma tryptophan tiers in foremost depression. J influence Disord 1989; sixteen: 27–31.
Asberg M, Thoren P, Traskman L, Bertilsson L, Ringberger V. ‘Serotonin depression’ – a biochemical subgroup within the affective disorders? Science 1976; 191: 478–480.
Sargent PA, Kjaer KH, Bench CJ, Rabiner EA, Messa C, Meyer J et al. brain serotonin1A receptor binding measured by way of positron emission tomography with [11C]way-100635: outcomes of melancholy and antidepressant medication. Arch Gen Psychiatry 2000; 57: 174–one hundred eighty.
Drevets WC, candid E, rate JC, Kupfer DJ, Holt D, Greer PJ et al. PET imaging of serotonin 1A receptor binding in melancholy. Biol Psychiatry 1999; forty six: 1375–1387.
Malison RT, cost LH, Berman R, van Dyck CH, Pelton GH, chippie L et al. decreased intellect serotonin transporter availability in main melancholy as measured by [123I]-2 beta-carbomethoxy-three beta-(4-iodophenyl)tropane and unique photon emission computed tomography. Biol Psychiatry 1998; forty four: 1090–1098.
Ellenbogen MA, younger SN, Dean P, Palmour RM, Benkelfat C. Acute tryptophan depletion in match green ladies with a family unit historical past of foremost affective sickness. Psychol Med 1999; 29: 35–forty six.
Klaassen T, Riedel WJ, van Someren A, Deutz NE, Honig A, van Praag HM. humor effects of 24-hour tryptophan depletion in in shape first-diploma relatives of sufferers with affective issues. Biol Psychiatry 1999; forty six: 489–497.
Moreno FA, Gelenberg AJ, Heninger GR, Potter RL, McKnight KM, Allen J et al. Tryptophan depletion and depressive vulnerability. Biol Psychiatry 1999; 46: 498–505.
Neumeister A, Nugent AC, Waldeck T, Geraci M, Schwarz M, Bonne O et al. Neural and behavioral responses to tryptophan depletion in unmedicated sufferers with remitted essential depressive disease and controls. Arch Gen Psychiatry 2004; sixty one: 765–773.
Kapitany T, Schindl M, Schindler SD, Hesselmann B, Fureder T, Barnas C et al. The citalopram challenge check in sufferers with essential melancholy and in robust controls. Psychiatry Res 1999; 88: seventy five–88.
Flory JD, Mann JJ, Manuck SB, Muldoon MF. recovery from major melancholy isn't associated with normalization of serotonergic feature. Biol Psychiatry 1998; forty three: 320–326.
Bhagwagar Z, Whale R, Cowen PJ. status and trait abnormalities in serotonin feature in most well-known depression. Br J Psychiatry 2002; one hundred eighty: 24–28.
van Praag HM. Can stress antecedent depression? Prog Neuropsychopharmacol Biol Psychiatry 2004; 28: 891–907.
Maes M, Meltzer HY. The serotonin hypothesis of major depression. In: prime FE, Kupfer DJ (eds). Psychopharmacology: The Fourth technology of growth. Raven Press, Ltd.: long island, 1995, pp 933–944.
Booij L, Van der Does W, Benkelfat C, Bremner JD, Cowen PJ, Fava M et al. Predictors of humor response to acute tryptophan depletion. A reanalysis. Neuropsychopharmacology 2002; 27: 852–861.
van Praag HM. erroneous cortisol/serotonin interplay. Psychopathological and biological characterisation of a brand new, hypothetical depression subtype (SeCA depression). Psychiatry Res 1996; sixty five: 143–157.
Neumeister A, Konstantinidis A, Stastny J, Schwarz MJ, Vitouch O, Willeit M et al. association between serotonin transporter gene promoter polymorphism (5HTTLPR) and behavioral responses to tryptophan depletion in felicitous girls with and with out household tradition of melancholy. Arch Gen Psychiatry 2002; 59: 613–620.
Sobczak S, Honig A, Nicolson NA, Riedel WJ. consequences of acute tryptophan depletion on temper and cortisol unlock in first-diploma loved ones of kind I and kind II bipolar patients and match matched controls. Neuropsychopharmacology 2002; 27: 834–842.
Sobczak S, Riedel WJ, Booij I, Aan Het Rot M, Deutz NE, Honig A. Cognition following acute tryptophan depletion: change between first-diploma relatives of bipolar sickness patients and matched robust handle volunteers. Psychol Med 2002; 32: 503–515.
Riedel WJ, Klaassen T, Schmitt JA. Tryptophan, mood, and cognitive characteristic. brain Behav Immun 2002; sixteen: 581–589.
Aberg-Wistedt A, Hasselmark L, Stain-Malmgren R, Aperia B, Kjellman BF, Mathe AA. Serotonergic ‘vulnerability’ in affective ailment: a dissect of the tryptophan depletion test and relationships between peripheral and central serotonin indexes in citalopram-responders. Acta Psychiatr Scand 1998; 97: 374–380.
Kendler KS, Davis CG, Kessler RC. The familial aggregation of ordinary psychiatric and pith utilize issues within the country wide Comorbidity Survey: a household historical past study. Br J Psychiatry 1997; 170: 541–548.
Sullivan PF, Neale MC, Kendler KS. Genetic epidemiology of most well-known depression: overview and meta-analysis. Am J Psychiatry 2000; 157: 1552–1562.
Sullivan PF, Wells JE, Joyce PR, Bushnell JA, Mulder RT, Oakley-Browne MA. family unit background of melancholy in sanatorium and neighborhood samples. J hold an consequence on Disord 1996; forty: 159–168.
Michalak EE, Wilkinson C, Hood okay, Dowrick C. Seasonal and nonseasonal depression: how finish they range? Symptom profile, medical and family tradition in a time-honored inhabitants sample. J influence Disord 2002; sixty nine: 185–192.
Stallings MC, Cherny SS, younger SE, Miles DR, Hewitt JK, Fulker DW. The familial aggregation of depressive indicators, antisocial conduct, and alcohol abuse. Am J Med Genet 1997; 74: 183–191.
Cadoret RJ, Winokur G, Langbehn D, Troughton E, Yates WR, Stewart MA. depression spectrum ailment, I: the position of gene-atmosphere interaction. Am J Psychiatry 1996; 153: 892–899.
Beck O, Borg S, Edman G, Fyro B, Oxenstierna G, Sedvall G. 5-hydroxytryptophol in human cerebrospinal fluid: conjugation, awareness gradient, relationship to 5-hydroxyindoleacetic acid, and influence of hereditary components. J Neurochem 1984; forty three: 58–61.
Oxenstierna G, Edman G, Iselius L, Oreland L, Ross SB, Sedvall G. Concentrations of monoamine metabolites within the cerebrospinal fluid of twins and unrelated individuals – a genetic analyze. J Psychiatr Res 1986; 20: 19–29.
Mann JJ, Huang YY, Underwood MD, Kassir SA, Oppenheim S, Kelly TM et al. A serotonin transporter gene promoter polymorphism (5-HTTLPR) and prefrontal cortical binding in essential melancholy and suicide. Arch Gen Psychiatry 2000; fifty seven: 729–738.
Lesch KP. Serotonergic gene expression and melancholy: implications for establishing novel antidepressants. J influence Disord 2001; sixty two: fifty seven–76.
Heils A, Teufel A, Petri S, Stober G, Riederer P, Bengel D et al. Allelic model of human serotonin transporter gene expression. J Neurochem 1996; sixty six: 2621–2624.
Lesch KP, Bengel D, Heils A, Sabol SZ, Greenberg BD, Petri S et al. affiliation of anxiety-connected qualities with a polymorphism in the serotonin transporter gene regulatory region. Science 1996; 274: 1527–1531.
Ohara okay, Nagai M, Tsukamoto T, Tani okay, Suzuki Y. practical polymorphism in the serotonin transporter promoter at the SLC6A4 locus and humor problems. Biol Psychiatry 1998; forty four: 550–554.
Minov C, Baghai TC, Schule C, Zwanzger P, Schwarz MJ, Zill P et al. Serotonin-2A-receptor and -transporter polymorphisms: lack of affiliation in sufferers with primary depression. Neurosci Lett 2001; 303: 119–122.
Joiner Jr TE, Johnson F, Soderstrom okay, Brown JS. Is there an affiliation between serotonin transporter gene polymorphism and family unit historical past of melancholy? J influence Disord 2003; seventy seven: 273–275.
Collier DA, Stober G, Li T, Heils A, Catalano M, Di Bella D et al. A novel functional polymorphism inside the promoter of the serotonin transporter gene: feasible duty in susceptibility to affective issues. Mol Psychiatry 1996; 1: 453–460.
Lesch KP, Mossner R. Genetically driven variation in serotonin uptake: is there a hyperlink to affective spectrum, neurodevelopmental, and neurodegenerative disorders? Biol Psychiatry 1998; 44: 179–192.
Hoefgen B, Schulze TG, Ohlraun S, von Widdern O, Hofels S, low M et al. The energy of sample size and homogenous sampling: association between the 5-HTTLPR serotonin transporter polymorphism and well-known depressive disorder. Biol Psychiatry 2005; fifty seven: 247–251.
Moreno FA, Rowe DC, Kaiser B, Chase D, Michaels T, Gelernter J et al. association between a serotonin transporter promoter vicinity polymorphism and temper response throughout tryptophan depletion. Mol Psychiatry 2002; 7: 213–216.
Lesch KP. edition of serotonergic gene expression: neurodevelopment and the complexity of response to psychopharmacologic medication. Eur Neuropsychopharmacol 2001; 11: 457–474.
Murphy DL, Li Q, Engel S, Wichems C, Andrews A, Lesch KP et al. Genetic perspectives on the serotonin transporter. intellect Res Bull 2001; fifty six: 487–494.
Tsai SJ, Wang YC, Hong CJ, Chiu HJ. association spy at of oestrogen receptor alpha gene polymorphism and suicidal behaviours in main depressive sickness. Psychiatr Genet 2003; 13: 19–22.
Yu YW, Tsai SJ, Chen TJ, Lin CH, Hong CJ. affiliation examine of the serotonin transporter promoter polymorphism and symptomatology and antidepressant response in primary depressive disorders. Mol Psychiatry 2002; 7: 1115–1119.
Durham LK, Webb SM, Milos PM, Clary CM, Seymour AB. The serotonin transporter polymorphism, 5HTTLPR, is associated with a quicker response time to sertraline in an aged population with predominant depressive disorder. Psychopharmacology (Berlin) 2004; 174: 525–529.
Pollock BG, Ferrell RE, Mulsant BH, Mazumdar S, Miller M, sweet RA et al. Allelic version within the serotonin transporter promoter influences onset of paroxetine medicine response in late-lifestyles depression. Neuropsychopharmacology 2000; 23: 587–590.
Smeraldi E, Zanardi R, Benedetti F, Di Bella D, Perez J, Catalano M. Polymorphism in the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine. Mol Psychiatry 1998; three: 508–511.
Neumeister A, younger T, Stastny J. Implications of genetic analysis on the position of the serotonin in depression: accent on the serotonin kind 1A receptor and the serotonin transporter. Psychopharmacology (Berln) 2004; 174: 512–524.
Lemonde S, Turecki G, Bakish D, Du L, Hrdina PD, Bown CD et al. Impaired repression at a 5-hydroxytryptamine 1A receptor gene polymorphism associated with essential depression and suicide. J Neurosci 2003; 23: 8788–8799.
Wu S, Comings DE. a standard C-1018G polymorphism in the human 5-HT1A receptor gene. Psychiatr Genet 1999; 9: 105–106.
Neumeister A, Bain E, Nugent AC, Carson RE, Bonne O, Luckenbaugh DA et al. decreased serotonin kind 1A receptor binding in panic sickness. J Neurosci 2004; 24: 589–591.
Harvey M, Shink E, Tremblay M, Gagne B, Raymond C, Labbe M et al. befriend for the involvement of TPH2 gene in affective problems. Mol Psychiatry 2004; 9: 980–981.
Bellivier F, Leboyer M, Courtet P, Buresi C, Beaufils B, Samolyk D et al. affiliation between the tryptophan hydroxylase gene and manic-depressive disease. Arch Gen Psychiatry 1998; fifty five: 33–37.
Walther DJ, Peter JU, Bashammakh S, Hortnagl H, Voits M, Fink H et al. Synthesis of serotonin by a 2nd tryptophan hydroxylase isoform. Science 2003; 299: 76.
Zhang X, Beaulieu JM, Sotnikova TD, Gainetdinov RR, Caron MG. Tryptophan hydroxylase-2 controls intellect serotonin synthesis. Science 2004; 305: 217.
Zhang X, Gainetdinov RR, Beaulieu JM, Sotnikova TD, Burch LH, Williams RB et al. Loss-of-feature mutation in tryptophan hydroxylase-2 recognized in unipolar predominant depression. Neuron 2005; forty five: 11–16.
Zill P, Baghai TC, Zwanzger P, Schule C, Eser D, Rupprecht R et al. SNP and haplotype evaluation of a novel tryptophan hydroxylase isoform (TPH2) gene deliver facts for association with principal melancholy. Mol Psychiatry 2004; 9: 1030–1036.
Cervo L, Canetta A, Calcagno E, Burbassi S, Sacchetti G, Caccia S et al. Genotype-elegant undertaking of tryptophan hydroxylase-2 determines the response to citalopram in a mouse model of melancholy. J Neurosci 2005; 25: 8165–8172.
Loehlin JC, McCrae RR, Costa PTJ, John OP. Heritables of typical and measure-certain add-ons of the huge five personality components. J Res personality 1998; 32: 431–453.
Boyce P, Parker G, Barnett B, Cooney M, Smith F. personality as a vulnerability aspect to depression. Br J Psychiatry 1991; 159: 106–114.
Kendler KS, Neale MC, Kessler RC, Heath AC, Eaves LJ. A longitudinal twin spy at of personality and predominant depression in ladies. Arch Gen Psychiatry 1993; 50: 853–862.
Hodgins S, Ellenbogen M. Neuroticism and depression. Br J Psychiatry 2003; 182: 79–eighty; author reply 80.
Duggan C, Sham P, Lee A, Minne C, Murray R. Neuroticism: a vulnerability marker for melancholy evidence from a household examine. J influence Disord 1995; 35: 139–143.
Kendler KS, Kuhn J, Prescott CA. The interrelationship of neuroticism, sex, and disturbing lifestyles routine within the prediction of episodes of foremost depression. Am J Psychiatry 2004; 161: 631–636.
Brown SL, Svrakic DM, Przybeck TR, Cloninger CR. the relationship of character to humor and anxiousness states: a dimensional method. J Psychiatr Res 1992; 26: 197–211.
Joffe RT, Bagby RM, Levitt AJ, Regan JJ, Parker JD. The Tridimensional personality Questionnaire in main melancholy. Am J Psychiatry 1993; 150: 959–960.
Strakowski SM, Dunayevich E, Keck Jr PE, McElroy SL. Affective status dependence of the Tridimensional character Questionnaire. Psychiatry Res 1995; fifty seven: 209–214.
Richter J, Eisemann M, Richter G. Temperament and personality throughout the route of unipolar depression amongst inpatients. Eur Arch Psychiatry Clin Neurosci 2000; 250: forty–forty seven.
Nelson EC, Cloninger CR, Przybeck TR, Csernansky JG. Platelet serotonergic markers and Tridimensional personality Questionnaire measures in a clinical sample. Biol Psychiatry 1996; 40: 271–278.
Hansenne M, Ansseau M. damage avoidance and serotonin. Biol Psychol 1999; 51: seventy seven–81.
Black KJ, Sheline YI. personality sickness ratings increase with efficient pharmacotherapy of depression. J influence Disord 1997; forty three: eleven–18.
Bond AJ. Neurotransmitters, temperament and gregarious functioning. Eur Neuropsychopharmacol 2001; 11: 261–274.
Tse WS, Bond AJ. Serotonergic involvement in the psychosocial dimension of character. J Psychopharmacol 2001; 15: 195–198.
Knutson B, Wolkowitz OM, Cole SW, Chan T, Moore EA, Johnson RC et al. Selective alteration of character and gregarious deportment by way of serotonergic intervention. Am J Psychiatry 1998; one hundred fifty five: 373–379.
Dunner DL, Schmaling KB, Hendrickson H, Becker J, Lehman A, Bea C. Cognitive therapy versus fluoxetine within the treatment of dysthymic disorder. melancholy 1996; 4: 34–forty one.
Chien AJ, Dunner DL. The Tridimensional personality Questionnaire in depression: status versus trait issues. J Psychiatr Res 1996; 30: 21–27.
Hansenne M, Pitchot W, Moreno AG, Reggers J, Machurot PY, Ansseau M. damage avoidance dimension of the Tridimensional character Questionnaire and serotonin-1A undertaking in depressed patients. Biol Psychiatry 1997; forty two: 959–961.
Peirson AR, Heuchert JW, Thomala L, Berk M, Plein H, Cloninger CR. Relationship between serotonin and the temperament and persona inventory. Psychiatry Res 1999; 89: 29–37.
Moresco FM, Dieci M, Vita A, Messa C, Gobbo C, Galli L et al. In vivo serotonin 5HT(2A) receptor binding and personality characteristics in suit topics: a positron emission tomography spy at. Neuroimage 2002; 17: 1470–1478.
Asberg M, Traskman L, Thoren P. 5-HIAA within the cerebrospinal fluid. A biochemical suicide predictor? Arch Gen Psychiatry 1976; 33: 1193–1197.
Linnoila M, Virkkunen M, Scheinin M, Nuutila A, Rimon R, Goodwin FK. Low cerebrospinal fluid 5-hydroxyindoleacetic acid concentration differentiates impulsive from nonimpulsive violent habits. life Sci 1983; 33: 2609–2614.
van Praag HM, Kahn RS, Asnis GM, Wetzler S, Brown SL, Bleich A et al. Denosologization of organic psychiatry or the specificity of 5-HT disturbances in psychiatric problems. J hold an consequence on Disord 1987; 13: 1–eight.
Asberg M. Neurotransmitters and suicidal conduct. The proof from cerebrospinal fluid reports. Ann ny Acad Sci 1997; 836: 158–181.
Higley JD, Suomi SJ, Linnoila M. CSF monoamine metabolite concentrations vary based on age, rearing, and sex, and are influenced by using the stressor of gregarious separation in rhesus monkeys. Psychopharmacology (Berlin) 1991; 103: 551–556.
Higley JD, Thompson WW, Champoux M, Goldman D, Hasert MF, Kraemer GW et al. Paternal and maternal genetic and environmental contributions to cerebrospinal fluid monoamine metabolites in rhesus monkeys (Macaca mulatta). Arch Gen Psychiatry 1993; 50: 615–623.
Higley JD, Linnoila M. Low valuable frightened tackle serotonergic undertaking is traitlike and correlates with impulsive habits. A nonhuman primate model investigating genetic and environmental influences on neurotransmission. Ann vast apple Acad Sci 1997; 836: 39–fifty six.
Piccinelli M, Wilkinson G. Gender variations in melancholy. well-known assessment. Br J Psychiatry 2000; 177: 486–492.
Weissman MM, Bland RC, Canino GJ, Faravelli C, Greenwald S, Hwu HG et al. pass-national epidemiology of primary melancholy and bipolar sickness. JAMA 1996; 276: 293–299.
Kessler RC, McGonagle KA, Swartz M, Blazer DG, Nelson CB. sex and depression in the countrywide Comorbidity Survey. I: lifetime incidence, chronicity and recurrence. J hold an consequence on Disord 1993; 29: 85–96.
Nolen-Hoeksema S. Gender changes in melancholy. Am Psychol Soc 2001; 10: 173–176.
Kornstein SG. Gender, depression, and antidepressant medicine. primary Psychiatry 2003; 10: 58–sixty one.
Dominguez R, Cruz-Morales SE, Carvalho MC, Xavier M, Brandao ML. sex modifications in serotonergic exercise in dorsal and median raphe nucleus. Physiol Behav 2003; eighty: 203–210.
Carlsson M, Carlsson A. A regional dissect of sex alterations in rat brain serotonin. Prog Neuropsychopharmacol Biol Psychiatry 1988; 12: 53–61.
Haleem DJ, Kennett GA, Curzon G. Hippocampal 5-hydroxytryptamine synthesis is greater in feminine rats than in males and greater lowered by way of the 5-HT1A agonist 8-OH-DPAT. J Neural Transm Gen Sect 1990; seventy nine: ninety three–one hundred and one.
Rosencrans JA. modifications in brain enviornment 5-hydroxytryptamine turnover and rearing habits in rats and mice of each sexes. Eur J Pharmacol 1970; 9: 379–382.
Klink R, Robichaud M, Debonnel G. Gender and gonadal repute modulation of dorsal raphe nucleus serotonergic neurons. half I: consequences of gender and being pregnant. Neuropharmacology 2002; forty three: 1119–1128.
Agren H, Mefford IN, Rudorfer MV, Linnoila M, Potter WZ. Interacting neurotransmitter methods. A non-experimental approach to the 5HIAA-HVA correlation in human CSF. J Psychiatr Res 1986; 20: 175–193.
younger SN, Gauthier S, Anderson GM, Purdy WC. Tryptophan, 5-hydroxyindolacetic acid and indoleacetic acid in human cerebrospinal fluid: interrelationship and the hold an impact on of age, sex, epilepsy and anticonvulsant medication. J Neurol Neurosurg Psychiatry 1980; forty three: 438–445.
Biver F, Lotstra F, Monclus M, Wikler D, Damhaut P, Mendlewicz J et al. sex change in 5HT2 receptor in the animate human mind. Neurosci Lett 1996; 204: 25–28.
Nishizawa S, Benkelfat C, younger SN, Leyton M, Mzengeza S, de Montigny C et al. adjustments between men and women in charges of serotonin synthesis in human brain. Proc Natl Acad Sci united states 1997; ninety four: 5308–5313.
Staley JK, Sanacora G, Tamagnan G, Maciejewski PK, Malison RT, Berman RM et al. sex alterations in diencephalon serotonin transporter availability in fundamental melancholy. Biol Psychiatry 2006; fifty nine: 40–47.
Osterlund MK, Hurd YL. Estrogen receptors within the human forebrain and the relation to neuropsychiatric disorders. Prog Neurobiol 2001; 64: 251–267.
Gundlah C, Simon LD, Auerbach SB. transformations in hypothalamic serotonin between estrous phases and gender: an in vivo microdialysis examine. intellect Res 1998; 785: 91–ninety six.
Maswood S, Truitt W, Hotema M, Caldarola-Pastuszka M, Uphouse L. Estrous cycle modulation of extracellular serotonin in mediobasal hypothalamus: role of the serotonin transporter and terminal autoreceptors. brain Res 1999; 831: 146–154.
Bethea CL, Gundlah C, Mirkes SJ. Ovarian steroid action within the serotonin neural gadget of macaques. Novartis discovered Symp 2000; 230: 112–one hundred thirty; dialogue 130–133.
Weigel NL. Steroid hormone receptors and their regulation by using phosphorylation. Biochem J 1996; 319(half three): 657–667.
Sumner BE, Fink G. Testosterone in addition to estrogen increases serotonin2A receptor mRNA and binding web page densities in the masculine rat mind. intellect Res Mol brain Res 1998; 59: 205–214.
Fink G, Sumner BE, McQueen JK, Wilson H, Rosie R. sex steroid control of temper, mental status and memory. Clin Exp Pharmacol Physiol 1998; 25: 764–775.
McEwen BS, Alves SE. Estrogen actions within the vital worried gadget. Endocr Rev 1999; 20: 279–307.
Joffe H, Cohen LS. Estrogen, serotonin, and temper disturbance: where is the therapeutic bridge? Biol Psychiatry 1998; forty four: 798–811.
Ostlund H, Keller E, Hurd YL. Estrogen receptor gene expression in relation to neuropsychiatric issues. Ann modern york Acad Sci 2003; 1007: 54–63.
Imwalle DB, Gustafsson JA, Rissman EF. lack of practical estrogen receptor beta influences nervousness habits and serotonin content in female mice. Physiol Behav 2005; eighty four: 157–163.
Rubinow DR, Schmidt PJ, Roca CA. Estrogen-serotonin interactions: implications for affective law. Biol Psychiatry 1998; 44: 839–850.
Markus CR. Interactions between stress, food and temper. In: Watson DaD F (ed). performance useful meals. Woodhead Publishing: Cambridge, 2003, pp 5–20.
Lopez JF, Akil H, Watson SJ. Neural circuits mediating stress. Biol Psychiatry 1999; 46: 1461–1471.
Connor TJ, Leonard BE. melancholy, stress and immunological activation: the role of cytokines in depressive issues. lifestyles Sci 1998; 62: 583–606.
Kofman O. The duty of prenatal stress in the etiology of developmental behavioural problems. Neurosci Biobehav Rev 2002; 26: 457–470.
Huizink AC, Mulder EJ, Buitelaar JK. Prenatal stress and risk for psychopathology: specific consequences or induction of everyday susceptibility? Psychol Bull 2004; one hundred thirty: 115–142.
Malarkey WB, Pearl DK, Demers LM, Kiecolt-Glaser JK, Glaser R. influence of academic stress and season on 24-hour insinuate concentrations of ACTH, cortisol, and beta-endorphin. Psychoneuroendocrinology 1995; 20: 499–508.
Anisman H, Merali Z. Cytokines, stress and depressive ailment: brain-immune interactions. Ann Med 2003; 35: 2–11.
Prickaerts J, Steckler T. effects of glucocorticoids on emotion and cognitive methods in animals. In: Steckler T, Kalin NH, Reul JMHM (eds). handbook of Stress and the mind. Elsevier: Amsterdam/London, 2005, pp 359–385.
de Kloet ER, Joels M, Holsboer F. Stress and the brain: from adaptation to disorder. Nat Rev Neurosci 2005; 6: 463–475.
Sachar EJ, Hellman L, Roffwarg HP, Halpern FS, Fukushima DK, Gallagher TF. Disrupted 24-hour patterns of cortisol secretion in psychotic melancholy. Arch Gen Psychiatry 1973; 28: 19–24.
Holsboer F. The corticosteroid receptor speculation of melancholy. Neuropsychopharmacology 2000; 23: 477–501.
Davis S, Heal DJ, Stanford SC. long-lasting results of an acute stress on the neurochemistry and duty of 5-hydroxytryptaminergic neurones within the mouse mind. Psychopharmacology (Berlin) 1995; 118: 267–272.
Maccari S, Darnaudery M, Morley-Fletcher S, Zuena AR, Cinque C, Van Reeth O. Prenatal stress and long-time epoch consequences: implications of glucocorticoid hormones. Neurosci Biobehav Rev 2003; 27: 119–127.
young AH, Goodwin GM, Dick H, Fink G. consequences of glucocorticoids on 5-HT1A presynaptic feature within the mouse. Psychopharmacology (Berlin) 1994; 114: 360–364.
Meijer OC, de Kloet ER. Corticosterone suppresses the expression of 5-HT1A receptor mRNA in rat dentate gyrus. Eur J Pharmacol 1994; 266: 255–261.
Anisman H, Zalcman S, Zacharko RM. The impact of stressors on immune and primary neurotransmitter exercise: bidirectional verbal exchange. Rev Neurosci 1993; four: 147–a hundred and eighty.
Porter RJ, Gallagher P, Watson S, green AH. Corticosteroid-serotonin interactions in depression: a assessment of the human facts. Psychopharmacology (Berlin) 2004; 173: 1–17.
Pariante CM, Makoff A, Lovestone S, Feroli S, Heyden A, Miller AH et al. Antidepressants boost glucocorticoid receptor duty in vitro via modulating the membrane steroid transporters. Br J Pharmacol 2001; 134: 1335–1343.
Robertson DA, Beattie JE, Reid IC, Balfour DJ. regulation of corticosteroid receptors within the rat brain: the duty of serotonin and stress. Eur J Neurosci 2005; 21: 1511–1520.
Lai M, McCormick JA, Chapman KE, Kelly PA, Seckl JR, Yau JL. Differential rules of corticosteroid receptors by way of monoamine neurotransmitters and antidepressant medication in simple hippocampal tradition. Neuroscience 2003; 118: 975–984.
Semont A, Fache M, Ouafik L, Hery M, Faudon M, Hery F. consequence of serotonin inhibition on glucocorticoid and mineralocorticoid expression in a considerable number of intellect buildings. Neuroendocrinology 1999; 69: 121–128.
Watanabe Y, Gould E, McEwen BS. Stress induces atrophy of apical dendrites of hippocampal CA3 pyramidal neurons. brain Res 1992; 588: 341–345.
Malberg JE, Duman RS. phone proliferation in grownup hippocampus is reduced through inescapable stress: reversal with the aid of fluoxetine treatment. Neuropsychopharmacology 2003; 28: 1562–1571.
Gould E, McEwen BS, Tanapat P, Galea LA, Fuchs E. Neurogenesis within the dentate gyrus of the adult tree shrew is regulated by psychosocial stress and NMDA receptor activation. J Neurosci 1997; 17: 2492–2498.
Magarinos AM, Verdugo JM, McEwen BS. continuous stress alters synaptic terminal structure in hippocampus. Proc Natl Acad Sci u . s . 1997; ninety four: 14002–14008.
McEwen BS, Magarinos AM. Stress consequences on morphology and performance of the hippocampus. Ann modern york Acad Sci 1997; 821: 271–284.
Sapolsky RM. Why stress is unhealthy in your mind. Science 1996; 273: 749–750.
Gould E, Tanapat P. Stress and hippocampal neurogenesis. Biol Psychiatry 1999; forty six: 1472–1479.
McEwen BS. insurance plot and harm from acute and persistent stress: allostasis and allostatic overload and relevance to the pathophysiology of psychiatric problems. Ann the vast apple Acad Sci 2004; 1032: 1–7.
Modell S, Lauer CJ, Schreiber W, Huber J, Krieg JC, Holsboer F. Hormonal response pattern in the mixed DEX-CRH verify is stable over time in subjects at towering familial risk for affective issues. Neuropsychopharmacology 1998; 18: 253–262.
McEwen BS. Stress and hippocampal plasticity. Annu Rev Neurosci 1999; 22: a hundred and five–122.
de Kloet ER, Sibug RM, Helmerhorst FM, Schmidt M. Stress, genes and the mechanism of programming the brain for later lifestyles. Neurosci Biobehav Rev 2005; 29: 271–281.
Morley-Fletcher S, Darnaudery M, Koehl M, Casolini P, Van Reeth O, Maccari S. Prenatal stress in rats predicts immobility deportment within the forced swim check. effects of a chronic medication with tianeptine. intellect Res 2003; 989: 246–251.
Watson JB, Mednick SA, Huttunen M, Wang X. Prenatal teratogens and the evolution of adult intellectual illness. Dev Psychopathol 1999; eleven: 457–466.
Weinstock M. Does prenatal stress impair coping and law of hypothalamic–pituitary–adrenal axis? Neurosci Biobehav Rev 1997; 21: 1–10.
Van den Hove DL, Steinbusch HW, Scheepens A, Van de Berg WD, Kooiman LA, Boosten BJ et al. Prenatal stress and neonatal rat brain development. Neuroscience 2006; 137: a hundred forty five–155.
Maccari S, Piazza PV, Kabbaj M, Barbazanges A, Simon H, Le Moal M. Adoption reverses the lengthy-time epoch impairment in glucocorticoid feedback prompted by prenatal stress. J Neurosci 1995; 15: 110–116.
Hayashi A, Nagaoka M, Yamada ok, Ichitani Y, Miake Y, Okado N. Maternal stress induces synaptic loss and developmental disabilities of offspring. Int J Dev Neurosci 1998; sixteen: 209–216.
Deminiere JM, Piazza PV, Guegan G, Abrous N, Maccari S, Le Moal M et al. expanded locomotor response to novelty and propensity to intravenous amphetamine self-administration in adult offspring of wired moms. intellect Res 1992; 586: a hundred thirty five–139.
Dugovic C, Maccari S, Weibel L, Turek FW, Van Reeth O. extreme corticosterone degrees in prenatally wired rats prognosticate persistent paradoxical sleep transformations. J Neurosci 1999; 19: 8656–8664.
Poltyrev T, Weinstock M. consequence of prenatal stress on opioid component of exploration in different experimental situations. Pharmacol Biochem Behav 1997; 58: 387–393.
Vallee M, Mayo W, Dellu F, Le Moal M, Simon H, Maccari S. Prenatal stress induces extreme nervousness and postnatal coping with induces low anxiousness in grownup offspring: correlation with stress-induced corticosterone secretion. J Neurosci 1997; 17: 2626–2636.
Bhatnagar S, Lee TM, Vining C. Prenatal stress differentially influences habituation of corticosterone responses to repeated stress in grownup masculine and female rats. Horm Behav 2005; forty seven: 430–438.
Carroll BJ, Curtis GC, Mendels J. Neuroendocrine rules in depression. II. Discrimination of depressed from nondepressed patients. Arch Gen Psychiatry 1976; 33: 1051–1058.
Mortola JF, Liu JH, Gillin JC, Rasmussen DD, Yen SS. Pulsatile rhythms of adrenocorticotropin (ACTH) and cortisol in women with endogenous depression: evidence for multiplied ACTH pulse frequency. J Clin Endocrinol Metab 1987; sixty five: 962–968.
Gaspar P, situations O, Maroteaux L. The developmental role of serotonin: information from mouse molecular genetics. Nat Rev Neurosci 2003; 4: 1002–1012.
Whitaker-Azmitia PM. Behavioral and cellular penalties of expanding serotonergic activity privilege through brain development: a role in autism? Int J Dev Neurosci 2005; 23: 75–eighty three.
Feenstra MG, van Galen H, Te Riele PJ, Botterblom MH, Mirmiran M. diminished hypothalamic serotonin stages in grownup rats handled neonatally with clomipramine. Pharmacol Biochem Behav 1996; 55: 647–652.
Shemer A, Whitaker-Azmitia PM, Azmitia EC. outcomes of prenatal 5-methoxytryptamine and parachlorophenylalanine on serotonergic uptake and deportment within the neonatal rat. Pharmacol Biochem Behav 1988; 30: 847–851.
Shemer AV, Azmitia EC, Whitaker-Azmitia PM. Dose-linked results of prenatal 5-methoxytryptamine (5-MT) on construction of serotonin terminal density and habits. brain Res Dev brain Res 1991; 59: fifty nine–sixty three.
Huether G, Thomke F, Adler L. Administration of tryptophan-enriched diets to pregnant rats retards the construction of the serotonergic tackle in their offspring. brain Res Dev brain Res 1992; 68: one hundred seventy five–181.
Akbari HM, Kramer HK, Whitaker-Azmitia PM, Spear LP, Azmitia EC. Prenatal cocaine publicity disrupts the edifice of the serotonergic equipment. intellect Res 1992; 572: fifty seven–sixty three.
Yan QS. decreased serotonin release and serotonin uptake sites in the rat nucleus accumbens and striatum after prenatal cocaine exposure. brain Res 2002; 929: 59–69.
Koprich JB, Chen EY, Kanaan NM, Campbell NG, Kordower JH, Lipton JW. Prenatal three,four-methylenedioxymethamphetamine (ecstasy) alters exploratory conduct, reduces monoamine metabolism, and increases forebrain tyrosine hydroxylase fiber density of teenybopper rats. Neurotoxicol Teratol 2003; 25: 509–517.
Whitaker-Azmitia PM, Zhang X, Clarke C. outcomes of gestational exposure to monoamine oxidase inhibitors in rats: preliminary behavioral and neurochemical studies. Neuropsychopharmacology 1994; 11: one hundred twenty five–132.
Owesson CA, Hopwood SE, Callado LF, Seif I, McLaughlin DP, Stamford JA. Altered presynaptic feature in monoaminergic neurons of monoamine oxidase-A knockout mice. Eur J Neurosci 2002; 15: 1516–1522.
Cabrera-Vera TM, Garcia F, Pinto W, Battaglia G. impact of prenatal fluoxetine (Prozac) exposure on brain serotonin neurons in prepubescent and adult masculine rat offspring. J Pharmacol Exp Ther 1997; 280: 138–one hundred forty five.
Cabrera-Vera TM, Battaglia G. Prenatal exposure to fluoxetine (Prozac) produces site-selected and age-elegant changes in intellect serotonin transporters in rat progeny: evidence from autoradiographic reports. J Pharmacol Exp Ther 1998; 286: 1474–1481.
Slotkin TA, Barnes GA, McCook EC, Seidler FJ. Programming of brainstem serotonin transporter construction by way of prenatal glucocorticoids. brain Res Dev brain Res 1996; 93: one hundred fifty five–161.
Muneoka ok, Mikuni M, Ogawa T, Kitera ok, Kamei okay, Takigawa M et al. Prenatal dexamethasone publicity alters intellect monoamine metabolism and adrenocortical response in rat offspring. Am J Physiol 1997; 273: R1669–R1675.
Owen D, Andrews MH, Matthews SG. Maternal adversity, glucocorticoids and programming of neuroendocrine duty and behaviour. Neurosci Biobehav Rev 2005; 29: 209–226.
Heim C, Nemeroff CB. The hold an impact on of early hostile experiences on intellect methods concerned in the pathophysiology of anxiety and affective disorders. Biol Psychiatry 1999; forty six: 1509–1522.
Heim C, Nemeroff CB. The role of childhood trauma within the neurobiology of temper and anxiety problems: preclinical and medical reports. Biol Psychiatry 2001; forty nine: 1023–1039.
Heim C, Plotsky PM, Nemeroff CB. magnitude of learning the contributions of early adversarial event to neurobiological findings in depression. Neuropsychopharmacology 2004; 29: 641–648.
Vazquez DM, Eskandari R, Zimmer CA, Levine S, Lopez JF. intellect 5-HT receptor gadget in the wired infant rat: implications for vulnerability to pith abuse. Psychoneuroendocrinology 2002; 27: 245–272.
Meaney MJ. Maternal care, gene expression, and the transmission of individual ameliorations in stress reactivity across generations. Annu Rev Neurosci 2001; 24: 1161–1192.
Gunnar MR, Donzella B. gregarious rules of the cortisol degrees in early human construction. Psychoneuroendocrinology 2002; 27: 199–220.
Sapolsky RM, Meaney MJ. Maturation of the adrenocortical stress response: neuroendocrine control mechanisms and the stress hyporesponsive duration. brain Res 1986; 396: sixty four–seventy six.
Gunnar MR. pleasant of early suffuse and buffering of neuroendocrine stress reactions: talents outcomes on the developing human mind. Prev Med 1998; 27: 208–211.
Gunnar MR, Brodersen L, Krueger k, Rigatuso J. Dampening of adrenocortical responses throughout infancy: normative changes and particular person differences. baby Dev 1996; 67: 877–889.
Ramsay DS, Lewis M. Developmental trade in newborn cortisol and behavioral response to inoculation. child Dev 1994; 65: 1491–1502.
Huot RL, Plotsky PM, Lenox RH, McNamara RK. Neonatal maternal separation reduces hippocampal mossy fiber density in grownup long Evans rats. brain Res 2002; 950: 52–63.
Meaney MJ, Diorio J, Francis D, Widdowson J, LaPlante P, Caldji C et al. Early environmental regulation of forebrain glucocorticoid receptor gene expression: implications for adrenocortical responses to stress. Dev Neurosci 1996; 18: 49–72.
Papaioannou A, Gerozissis okay, Prokopiou A, Bolaris S, Stylianopoulou F. sex modifications in the outcomes of neonatal handling on the animal's response to emphasize and the vulnerability for depressive behaviour. Behav intellect Res 2002; 129: 131–139.
Ruedi-Bettschen D, Pedersen EM, Feldon J, Pryce CR. Early deprivation under inevitable situations results in reduced pastime in reward in adulthood in Wistar rats. Behav intellect Res 2005; 156: 297–310.
Ruedi-Bettschen D, Feldon J, Pryce CR. The impaired coping triggered by way of early deprivation is reversed with the aid of chronic fluoxetine medicine in grownup fischer rats. Behav Pharmacol 2004; 15: 413–421.
Bhatnagar S, Meaney MJ. Hypothalamic-pituitary-adrenal duty in persistent intermittently bloodless-stressed neonatally dealt with and non dealt with rats. J Neuroendocrinol 1995; 7: 97–108.
Huot RL, Gonzalez ME, Ladd CO, Thrivikraman KV, Plotsky PM. Foster litters preclude hypothalamic–pituitary–adrenal axis sensitization mediated by neonatal maternal separation. Psychoneuroendocrinology 2004; 29: 279–289.
Sutanto W, Rosenfeld P, de Kloet ER, Levine S. lengthy-time epoch outcomes of neonatal maternal deprivation and ACTH on hippocampal mineralocorticoid and glucocorticoid receptors. intellect Res Dev intellect Res 1996; ninety two: 156–163.
Karten YJ, Olariu A, Cameron HA. Stress in formative years inhibits neurogenesis in adulthood. traits Neurosci 2005; 28: 171–172.
Sapolsky RM. Is impaired neurogenesis apposite to the affective signs of depression? Biol Psychiatry 2004; fifty six: 137–139.
Malberg JE, Eisch AJ, Nestler EJ, Duman RS. chronic antidepressant treatment raises neurogenesis in grownup rat hippocampus. J Neurosci 2000; 20: 9104–9110.
Mirescu C, Peters JD, Gould E. formative years journey alters response of adult neurogenesis to stress. Nat Neurosci 2004; 7: 841–846.
Anisman H, Merali Z, Hayley S. Sensitization associated with stressors and cytokine treatments. intellect Behav Immun 2003; 17: 86–ninety three.
Anisman H, Hayley S, Turrin N, Merali Z. Cytokines as a stressor: implications for depressive illness. Int J Neuropsychopharmacol 2002; 5: 357–373.
Capuron L, Dantzer R. Cytokines and depression: the exigency for a modern paradigm. brain Behav Immun 2003; 17(Suppl 1): S119–S124.
Leonard BE, song C. Stress, melancholy, and the position of cytokines. Adv Exp Med Biol 1999; 461: 251–265.
Watkins LR, Nguyen KT, Lee JE, Maier SF. Dynamic legislation of proinflammatory cytokines. Adv Exp Med Biol 1999; 461: 153–178.
Schiepers OJ, Wichers MC, Maes M. Cytokines and major depression. Prog Neuropsychopharmacol Biol Psychiatry 2005; 29: 201–217.
Kronfol Z, Silva Jr J, Greden J, Dembinski S, Gardner R, Carroll B. Impaired lymphocyte characteristic in depressive ailment. actuality Sci 1983; 33: 241–247.
Irwin M, Gillin JC. Impaired herbal killer phone undertaking among depressed sufferers. Psychiatry Res 1987; 20: 181–182.
Maes M. proof for an immune response in main melancholy: a evaluation and hypothesis. Prog Neuropsychopharmacol Biol Psychiatry 1995; 19: eleven–38.
Maes M. essential depression and activation of the inflammatory response equipment. Adv Exp Med Biol 1999; 461: 25–forty six.
Nunes SO, Reiche EM, Morimoto HK, Matsuo T, Itano EN, Xavier EC et al. Immune and hormonal recreation in adults suffering from melancholy. Braz J Med Biol Res 2002; 35: 581–587.
Yirmiya R. melancholy in medical disease: the role of the immune gadget. West J Med 2000; 173: 333–336.
Wright CE, Strike computing device, Brydon L, Steptoe A. Acute irritation and impecunious mood: mediation by means of cytokine activation. brain Behav Immun 2005; 19: 345–350.
Reichenberg A, Yirmiya R, Schuld A, Kraus T, Haack M, Morag A et al. Cytokine-linked emotional and cognitive disturbances in people. Arch Gen Psychiatry 2001; fifty eight: 445–452.
Strike pc, Wardle J, Steptoe A. mild acute inflammatory stimulation induces evanescent sinister mood. J Psychosom Res 2004; 57: 189–194.
Bonaccorso S, Puzella A, Marino V, Pasquini M, Biondi M, Artini M et al. Immunotherapy with interferon-alpha in sufferers suffering from persistent hepatitis C induces an intercorrelated stimulation of the cytokine network and an increase in depressive and anxiousness symptoms. Psychiatry Res 2001; one hundred and five: 45–fifty five.
Yirmiya R, Weidenfeld J, Pollak Y, Morag M, Morag A, Avitsur R et al. Cytokines, ‘depression as a result of a ordinary scientific situation,’ and antidepressant medication. Adv Exp Med Biol 1999; 461: 283–316.
Plata-Salaman CR. Cytokines and anorexia: a quick overview. Semin Oncol 1998; 25: 64–seventy two.
Wichers MC, Maes M. The position of indoleamine 2,three-dioxygenase (IDO) in the pathophysiology of interferon-alpha-induced depression. J Psychiatry Neurosci 2004; 29: 11–17.
Heyes MP, Saito k, Crowley JS, Davis LE, Demitrack MA, Der M et al. Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disorder. brain 1992; one hundred fifteen(half 5): 1249–1273.
Stone TW, Darlington LG. Endogenous kynurenines as aims for drug discovery and building. Nat Rev Drug Discov 2002; 1: 609–620.
Maes M, Verkerk R, Bonaccorso S, Ombelet W, Bosmans E, Scharpe S. Depressive and anxiety indicators within the early puerperium are concerning elevated degradation of tryptophan into kynurenine, a phenomenon which is related to immune activation. actuality Sci 2002; seventy one: 1837–1848.
Kubera M, Maes M. Serotonin-immune interactions in fundamental melancholy. In: Patterson PH, Kordon C, Christen Y (eds). Neuroimmune Interactions in Neurologic and Psychiatric problems. Springer Verlag: modern york, 2000, pp seventy nine–88.
Maes M, Capuron L, Ravaud A, Gualde N, Bosmans E, Egyed B et al. diminished serum dipeptidyl peptidase IV endeavor is associated with depressive indicators and cytokine creation in cancer sufferers receiving interleukin-2-primarily based immunotherapy. Neuropsychopharmacology 2001; 24: 130–140.
Bonaccorso S, Marino V, Puzella A, Pasquini M, Biondi M, Artini M et al. improved depressive ratings in patients with hepatitis C receiving interferon-alpha-based mostly immunotherapy are related to interferon-alpha-triggered adjustments within the serotonergic system. J Clin Psychopharmacol 2002; 22: 86–ninety.
Bonaccorso S, Marino V, Biondi M, Grimaldi F, Ippoliti F, Maes M. melancholy brought about via medicine with interferon-alpha in patients affected by hepatitis C virus. J hold an consequence on Disord 2002; seventy two: 237–241.
Ramamoorthy S, Ramamoorthy JD, Prasad PD, Bhat GK, Mahesh VB, Leibach FH et al. regulation of the human serotonin transporter by means of interleukin-1 beta. Biochem Biophys Res Commun 1995; 216: 560–567.
Mossner R, Heils A, Stober G, Okladnova O, Daniel S, Lesch KP. Enhancement of serotonin transporter feature by tumor necrosis aspect alpha but no longer by using interleukin-6. Neurochem Int 1998; 33: 251–254.
Morikawa O, Sakai N, Obara H, Saito N. results of interferon-alpha, interferon-gamma and cAMP on the transcriptional law of the serotonin transporter. Eur J Pharmacol 1998; 349: 317–324.
McDonald WM, Richard IH, DeLong MR. prevalence, etiology, and remedy of melancholy in Parkinson's disease. Biol Psychiatry 2003; fifty four: 363–375.
Hayley S, Poulter MO, Merali Z, Anisman H. The pathogenesis of scientific depression: stressor- and cytokine-induced ameliorations of neuroplasticity. Neuroscience 2005; one hundred thirty five: 659–678.
Mattson MP, Maudsley S, Martin B. BDNF and 5-HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative issues. tendencies Neurosci 2004; 27: 589–594.
Hayley S, Kelly O, Anisman H. Murine tumor necrosis ingredient-alpha sensitizes plasma corticosterone pastime and the manifestation of shock: modulation by histamine. J Neuroimmunol 2002; 131: 60–sixty nine.
Schmidt ED, Janszen AW, Wouterlood FG, Tilders FJ. Interleukin-1-caused long-lasting adjustments in hypothalamic corticotropin-releasing hormone (CRH) – neurons and hyperresponsiveness of the hypothalamus-pituitary-adrenal axis. J Neurosci 1995; 15: 7417–7426.
Tilders FJ, Schmidt ED, de Goeij DC. Phenotypic plasticity of CRF neurons throughout stress. Ann ny Acad Sci 1993; 697: 39–52.
Tilders FJ, Schmidt ED. go-sensitization between immune and non-immune stressors. a role within the etiology of melancholy? Adv Exp Med Biol 1999; 461: 179–197.
Simmons DA, Broderick PA. Cytokines, stressors, and medical melancholy: augmented adaptation responses underlie depression pathogenesis. Prog Neuropsychopharmacol Biol Psychiatry 2005; 29: 793–807.
Valentine advert, Meyers CA, Kling MA, Richelson E, Hauser P. temper and cognitive side effects of interferon-alpha therapy. Semin Oncol 1998; 25: 39–forty seven.
Capuron L, Ravaud A. Prediction of the depressive consequences of interferon alfa remedy by using the affected person's initial affective state. N Engl J Med 1999; 340: 1370.
Verheyden SL, Hadfield J, Calin T, Curran HV. Sub-acute results of MDMA (+/−3,four-methylenedioxymethamphetamine, ‘ecstasy’) on mood: evidence of gender changes. Psychopharmacology (Berlin) 2002; 161: 23–31.
McKenna DJ, Peroutka SJ. Neurochemistry and neurotoxicity of three,4-methylenedioxymethamphetamine (MDMA, ‘ecstasy’). J Neurochem 1990; 54: 14–22.
Schmidt CJ. Neurotoxicity of the psychedelic amphetamine, methylenedioxymethamphetamine. J Pharmacol Exp Ther 1987; 240: 1–7.
Ricaurte GA, Yuan J, McCann UD. 3,4-Methylenedioxymethamphetamine (‘ecstasy’)-triggered serotonin neurotoxicity: reviews in animals. Neuropsychobiology 2000; forty two: 5–10.
Reneman L, Booij J, de Bruin k, Reitsma JB, de Wolff FA, Gunning WB et al. outcomes of dose, sex, and long-time epoch abstention from utilize on toxic effects of MDMA (ecstasy) on brain serotonin neurons. Lancet 2001; 358: 1864–1869.
Semple DM, Ebmeier KP, Glabus MF, O'Carroll RE, Johnstone EC. decreased in vivo binding to the serotonin transporter in the cerebral cortex of MDMA (‘ecstasy’) users. Br J Psychiatry 1999; one hundred seventy five: sixty three–69.
Reneman L, Lavalaye J, Schmand B, de Wolff FA, van den Brink W, den Heeten GJ et al. Cortical serotonin transporter density and verbal remembrance in individuals who stopped the utilize of three,four-methylenedioxymethamphetamine (MDMA or ‘ecstasy’): preliminary findings. Arch Gen Psychiatry 2001; 58: 901–906.
Curran HV, Verheyden SL. Altered response to tryptophan supplementation after long-term abstention from MDMA (ecstasy) is tremendously correlated with human remembrance function. Psychopharmacology (Berlin) 2003; 169: 91–103.
Hatzidimitriou G, McCann UD, Ricaurte GA. Altered serotonin innervation patterns within the forebrain of monkeys treated with (+/−)3,four-methylenedioxymethamphetamine seven years up to now: factors influencing irregular recovery. J Neurosci 1999; 19: 5096–5107.
Scheffel U, Szabo Z, Mathews WB, Finley PA, Dannals RF, Ravert HT et al. In vivo detection of short- and lengthy-term MDMA neurotoxicity – a positron emission tomography spy at in the residing baboon brain. Synapse 1998; 29: 183–192.
Thomasius R, Petersen okay, Buchert R, Andresen B, Zapletalova P, Wartberg L et al. temper, cognition and serotonin transporter availability in existing and former ecstasy (MDMA) clients. Psychopharmacology (Berlin) 2003; 167: eighty five–96.
Gerra G, Zaimovic A, Ferri M, Zambelli U, Timpano M, Neri E et al. long-lasting effects of (+/−)three,four-methylenedioxymethamphetamine (ecstasy) on serotonin gadget characteristic in humans. Biol Psychiatry 2000; 47: 127–136.
de Win MM, Reneman L, Reitsma JB, den Heeten GJ, Booij J, van den Brink W. temper issues and serotonin transporter density in ecstasy users – the impact of lengthy-term abstention, dose, and gender. Psychopharmacology (Berlin) 2004; 173: 376–382.
Reneman L, Booij J, Schmand B, van den Brink W, Gunning B. remembrance disturbances in ‘ecstasy’ clients are correlated with an altered brain serotonin neurotransmission. Psychopharmacology (Berlin) 2000; 148: 322–324.
Gerra G, Zaimovic A, Giucastro G, Maestri D, Monica C, Sartori R et al. Serotonergic characteristic after (+/−)three,4-methylene-dioxymethamphetamine (‘ecstasy’) in people. Int Clin Psychopharmacol 1998; 13: 1–9.
Gamma A, Frei E, Lehmann D, Pascual-Marqui RD, Hell D, Vollenweider FX. humor status and intellect electric powered undertaking in ecstasy clients. Neuroreport 2000; eleven: 157–162.
Gamma A, Buck A, Berthold T, Vollenweider FX. No incompatibility in brain activation privilege through cognitive performance between ecstasy (three,four-methylenedioxymethamphetamine) users and handle topics: a [H2(15)O]-positron emission tomography analyze. J Clin Psychopharmacol 2001; 21: 66–seventy one.
MacInnes N, Handley SL, Harding GF. Former persistent methylenedioxymethamphetamine (MDMA or ecstasy) clients file light depressive signs. J Psychopharmacol 2001; 15: 181–186.
Morgan MJ, McFie L, Fleetwood H, Robinson JA. ecstasy (MDMA): are the psychological problems associated with its utilize reversed by way of extended abstinence? Psychopharmacology (Berlin) 2002; 159: 294–303.
Guillot C, Greenway D. recreational ecstasy utilize and melancholy. J Psychopharmacol 2006; 20: 411–416.
Hesselbrock MN, Meyer RE, Keener JJ. Psychopathology in hospitalized alcoholics. Arch Gen Psychiatry 1985; forty two: 1050–1055.
Powell BJ, Penick EC, Othmer E, Bingham SF, Rice AS. episode of further psychiatric syndromes among masculine alcoholics. J Clin Psychiatry 1982; 43: 404–407.
LeMarquand D, Pihl RO, Benkelfat C. Serotonin and alcohol consumption, abuse, and dependence: findings of animal studies. Biol Psychiatry 1994; 36: 395–421.
LeMarquand D, Pihl RO, Benkelfat C. Serotonin and alcohol intake, abuse, and dependence: medical proof. Biol Psychiatry 1994; 36: 326–337.
Oscar-Berman M, Shagrin B, Evert DL, Epstein C. Impairments of intellect and behavior: the neurological outcomes of alcohol. Alcohol fitness Res World 1997; 21: sixty five–75.
Halliday G, Ellis J, Heard R, Caine D, Harper C. Brainstem serotonergic neurons in chronic alcoholics with and with out the remembrance impairment of Korsakoff's psychosis. J Neuropathol Exp Neurol 1993; fifty two: 567–579.
Heinz A, Ragan P, Jones DW, Hommer D, Williams W, Knable MB et al. decreased significant serotonin transporters in alcoholism. Am J Psychiatry 1998; 155: 1544–1549.
Badawy AA, Evans M. The position of free serum tryptophan in the biphasic consequence of acute ethanol administration on the concentrations of rat brain tryptophan, 5-hydroxytryptamine and 5-hydroxyindol-three-ylacetic acid. Biochem J 1976; a hundred and sixty: 315–324.
Morland J, Stowell L, Gjerde H. Ethanol raises rat liver tryptophan oxygenase: proof for corticosterone mediation. Alcohol 1985; 2: 255–259.
Vaillant GE, Clark W, Cyrus C, Milofsky ES, Kopp J, Wulsin VW et al. potential dissect of alcoholism medication. Eight-yr observe-up. Am J Med 1983; 75: 455–463.
Degenhardt L, hall W, Lynskey M. Exploring the association between cannabis utilize and melancholy. addiction 2003; 98: 1493–1504.
Egashira N, Mishima k, Katsurabayashi S, Yoshitake T, Matsumoto Y, Ishida J et al. Involvement of 5-hydroxytryptamine neuronal device in delta(9)-tetrahydrocannabinol-brought about impairment of spatial memory. Eur J Pharmacol 2002; 445: 221–229.
Hill MN, solar JC, Tse MT, Gorzalka BB. Altered responsiveness of serotonin receptor subtypes following long-term cannabinoid medicine. Int J Neuropsychopharmacol 2006; 9: 277–286.
Reith ME, Sershen H, Allen DL, Lajtha A. A component of [3H]cocaine binding in brain is associated with serotonergic neurons. Mol Pharmacol 1983; 23: 600–606.
Ritz MC, Cone EJ, Kuhar MJ. Cocaine inhibition of ligand binding at dopamine, norepinephrine and serotonin transporters: a structure-exercise examine. life Sci 1990; 46: 635–645.
Levy advert, Baumann MH, Van de Kar LD. Monoaminergic legislation of neuroendocrine feature and its change with the aid of cocaine. entrance Neuroendocrinol 1994; 15: 85–156.
Gawin FH, Kleber HD. continence symptomatology and psychiatric analysis in cocaine abusers. medical observations. Arch Gen Psychiatry 1986; forty three: 107–113.
Baumann MH, Rothman RB. Repeated cocaine administration reduces 5-HT1A-mediated prolactin secretion in rats. Neurosci Lett 1995; 193: 9–12.
Baumann MH, Rothman RB. differences in serotonergic responsiveness during cocaine withdrawal in rats: similarities to fundamental melancholy in people. Biol Psychiatry 1998; forty four: 578–591.
Hariri AR, Holmes A. Genetics of emotional legislation: the role of the serotonin transporter in neural characteristic. trends Cogn Sci 2006; 10: 182–191.
Caspi A, Sugden k, Moffitt TE, Taylor A, Craig IW, Harrington H et al. influence of life stress on depression: moderation with the aid of a polymorphism in the 5-HTT gene. Science 2003; 301: 386–389.
Kendler KS, Kuhn JW, Vittum J, Prescott CA, Riley B. The interaction of annoying life hobbies and a serotonin transporter polymorphism within the prediction of episodes of main melancholy: a replication. Arch Gen Psychiatry 2005; sixty two: 529–535.
Bennett AJ, Lesch KP, Heils A, lengthy JC, Lorenz JG, Shoaf SE et al. Early event and serotonin transporter gene edition interact to influence primate CNS characteristic. Mol Psychiatry 2002; 7: 118–122.
Hariri AR, Mattay VS, Tessitore A, Kolachana B, Fera F, Goldman D et al. Serotonin transporter genetic model and the response of the human amygdala. Science 2002; 297: four hundred–403.
Hariri AR, Drabant EM, Munoz KE, Kolachana BS, Mattay VS, Egan MF et al. A susceptibility gene for affective disorders and the response of the human amygdala. Arch Gen Psychiatry 2005; sixty two: 146–152.
Heinz A, Braus DF, Smolka MN, Wrase J, Puls I, Hermann D et al. Amygdala-prefrontal coupling depends on a genetic edition of the serotonin transporter. Nat Neurosci 2005; 8: 20–21.
Roiser JP, cook LJ, Cooper JD, Rubinsztein DC, Sahakian BJ. affiliation of a functional polymorphism in the serotonin transporter gene with abnormal emotional processing in ecstasy clients. Am J Psychiatry 2005; 162: 609–612.
Rubinsztein JS, Rogers RD, Riedel WJ, Mehta MA, Robbins TW, Sahakian BJ. Acute dietary tryptophan depletion impairs protection of ‘affective set’ and delayed visual focus in match volunteers. Psychopharmacology (Berlin) 2001; 154: 319–326.
Heinz A, Jones DW, Mazzanti C, Goldman D, Ragan P, Hommer D et al. A relationship between serotonin transporter genotype and in vivo protein expression and alcohol neurotoxicity. Biol Psychiatry 2000; forty seven: 643–649.
Little KY, McLaughlin DP, Zhang L, Livermore CS, Dalack GW, McFinton PR et al. Cocaine, ethanol, and genotype results on human midbrain serotonin transporter binding sites and mRNA levels. Am J Psychiatry 1998; a hundred and fifty five: 207–213.
Schuckit MA, Mazzanti C, Smith TL, Ahmed U, Radel M, Iwata N et al. Selective genotyping for the role of 5-HT2A, 5-HT2C, and GABA alpha 6 receptors and the serotonin transporter within the degree of response to alcohol: a pilot examine. Biol Psychiatry 1999; forty five: 647–651.
Greenberg BD, Li Q, Lucas FR, Hu S, Sirota LA, Benjamin J et al. association between the serotonin transporter promoter polymorphism and character traits in a primarily feminine inhabitants sample. Am J Med Genet 2000; ninety six: 202–216.
Mazzanti CM, Lappalainen J, lengthy JC, Bengel D, Naukkarinen H, Eggert M et al. position of the serotonin transporter promoter polymorphism in anxiousness-related features. Arch Gen Psychiatry 1998; fifty five: 936–940.
Van Gestel S, Forsgren T, Claes S, Del-Favero J, Van Duijn CM, Sluijs S et al. Epistatic consequence of genes from the dopamine and serotonin systems on the temperament traits of novelty in search of and harm avoidance. Mol Psychiatry 2002; 7: 448–450.
Kendler KS, Karkowski LM, Prescott CA. Causal relationship between traumatic lifestyles pursuits and the onset of major melancholy. Am J Psychiatry 1999; 156: 837–841.
Weiss EL, Longhurst JG, Mazure CM. Childhood sexual maltreat as a risk ingredient for melancholy in girls: psychosocial and neurobiological correlates. Am J Psychiatry 1999; 156: 816–828.
McCormick CM, Smythe JW, Sharma S, Meaney MJ. sex-certain effects of prenatal stress on hypothalamic-pituitary-adrenal responses to stress and brain glucocorticoid receptor density in grownup rats. brain Res Dev intellect Res 1995; 84: 55–61.
Szuran TF, Pliska V, Pokorny J, Welzl H. Prenatal stress in rats: outcomes on plasma corticosterone, hippocampal glucocorticoid receptors, and maze efficiency. Physiol Behav 2000; seventy one: 353–362.
Weinstock M, Matlina E, Maor GI, Rosen H, McEwen BS. Prenatal stress selectively alters the reactivity of the hypothalamic-pituitary adrenal tackle within the female rat. intellect Res 1992; 595: 195–200.
Cutler S, Nolen-Hoeksema S. Accounting for sex ameliorations in depression through feminine victimization: childhood sexual abuse. intercourse Roles 1991; 24: 425–438.
Matud MP. Gender differencesin stress and coping styles. personality individual compass 2004; 37: 1401–1415.
Grabe HJ, Lange M, Wolff B, Volzke H, Lucht M, Freyberger HJ et al. mental and actual misery is modulated through a polymorphism within the 5-HT transporter gene interacting with gregarious stressors and continuous disorder burden. Mol Psychiatry 2005; 10: 220–224.
Brewin CR. Cognitive processing of opposed experiences. Int Rev Psychiatry 1996; eight: 333–339.
Hanninen V, Aro H. intercourse differences in coping and depression amongst green adults. Soc Sci Med 1996; 43: 1453–1460.
Miller SM, Kirsch N. intercourse differences in cognitive dealing with stress. In: Barnett RC, Biener L, Baruch GK (eds). Gender & Stress. The Free Press: vast apple, 1987, pp 278–307.
Ptacek JT, Smith RE, Zanas J. Gender, appraisal, and coping: a longitudinal evaluation. J own 1992; 60: 747–770.
Shors TJ, Miesegaes G. Testosterone in utero and at delivery dictates how disturbing adventure will hold an consequence on gaining erudition of in maturity. Proc Natl Acad Sci usa 2002; ninety nine: 13955–13960.
timber GE, Beylin AV, Shors TJ. The contribution of adrenal and reproductive hormones to the opposing effects of stress on trace conditioning in men versus ladies. Behav Neurosci 2001; 115: a hundred seventy five–187.
Kennett GA, Chaouloff F, Marcou M, Curzon G. feminine rats are greater prone than males in an animal model of depression: the feasible role of serotonin. brain Res 1986; 382: 416–421.
Liechti ME, Gamma A, Vollenweider FX. Gender adjustments in the subjective consequences of MDMA. Psychopharmacology (Berlin) 2001; 154: 161–168.
McCann UD, Ridenour A, Shaham Y, Ricaurte GA. Serotonin neurotoxicity after (+/−)three,4-methylenedioxymethamphetamine (MDMA; ‘ecstasy’): a managed examine in people. Neuropsychopharmacology 1994; 10: 129–138.
Brunner D, chicken R. Insights into the neurobiology of impulsive conduct from serotonin receptor knockout mice. Ann ny Acad Sci 1997; 836: eighty one–105.
Ramboz S, Saudou F, Amara DA, Belzung C, Segu L, Misslin R et al. 5-HT1B receptor knock out – behavioral penalties. Behav brain Res 1996; 73: 305–312.
Lesch KP, Mossner R. Knockout corner: 5-HT(1A) receptor inactivation: anxiety or depression as a murine journey. Int J Neuropsychopharmcol 1999; 2: 327–331.
Zhuang X, low C, Santarelli L, Compan V, Trillat AC, fowl R. Altered emotional states in knockout mice lacking 5-HT1A or 5-HT1B receptors. Neuropsychopharmacology 1999; 21: 52S–60S.
Bell C, Abrams J, Nutt D. Tryptophan depletion and its implications for psychiatry. Br J Psychiatry 2001; 178: 399–405.
young SN, Leyton M. The duty of serotonin in human humor and gregarious interplay. perception from altered tryptophan stages. Pharmacol Biochem Behav 2002; 71: 857–865.
Gala RR. The physiology and mechanisms of the stress-triggered changes in prolactin secretion in the rat. lifestyles Sci 1990; 46: 1407–1420.
Van de Kar LD, Rittenhouse PA, Li Q, Levy advert. Serotonergic law of renin and prolactin secretion. Behav brain Res 1996; 73: 203–208.
Cowen PJ, Charig EM. Neuroendocrine responses to intravenous tryptophan in major melancholy. Arch Gen Psychiatry 1987; 44: 958–966.
MacIndoe JH, Turkington RW. Stimulation of human prolactin secretion by using intravenous infusion of L-tryptophan. J Clin manufacture investments 1973; fifty two: 1972–1978.
Clemens JA, Bennett DR, Fuller RW. The impact of a tryptophan-free food plot on prolactin and corticosterone release by using serotonergic stimuli. Horm Metab Res 1980; 12: 35–38.
Delgado PL, Charney DS, rate LH, Landis H, Heninger GR. Neuroendocrine and behavioral outcomes of dietary tryptophan restriction in in shape topics. life Sci 1989; forty five: 2323–2332.
Riedel WJ, Klaassen T, Griez E, Honig A, Menheere PP, van Praag HM. Dissociable hormonal, cognitive and humor responses to neuroendocrine challenge: evidence for receptor-particular serotonergic dysregulation in depressed mood. Neuropsychopharmacology 2002; 26: 358–367.
Charney DS, Heninger GR, Reinhard Jr JF, Sternberg DE, Hafstead KM. The impact of IV L-tryptophan on prolactin, growth hormone, and humor in robust topics. Psychopharmacology (Berlin) 1982; 78: 38–43.
Siever LJ, Murphy DL, Slater S, de la Vega E, Lipper S. Plasma prolactin adjustments following fenfluramine in depressed sufferers in comparison to controls: an evaluation of primary serotonergic responsivity in depression. actuality Sci 1984; 34: 1029–1039.
Asnis GM, Eisenberg J, van Praag HM, Lemus CZ, Friedman JM, Miller AH. The neuroendocrine response to fenfluramine in depressives and commonplace controls. Biol Psychiatry 1988; 24: 117–120.
Maes M, D'Hondt P, Suy E, Minner B, Vandervorst C, Raus J. HPA-axis hormones and prolactin responses to dextro-fenfluramine in depressed sufferers and suit controls. Prog Neuropsychopharmacol Biol Psychiatry 1991; 15: 781–790.
Lichtenberg P, Shapira B, Gillon D, Kindler S, Cooper TB, Newman ME et al. Hormone responses to fenfluramine and placebo problem in endogenous depression. Psychiatry Res 1992; 43: 137–146.
O'Keane V, Dinan TG. Prolactin and cortisol responses to D-fenfluramine in essential melancholy: facts for diminished responsivity of crucial serotonergic characteristic. Am J Psychiatry 1991; 148: 1009–1015.
Meltzer HY, Flemming R, Robertson A. The consequence of buspirone on prolactin and increase hormone secretion in man. Arch Gen Psychiatry 1983; forty: 1099–1102.
Charney DS, Woods SW, Goodman WK, Heninger GR. Serotonin feature in anxiousness. II. outcomes of the serotonin agonist MCPP in panic sickness sufferers and felicitous topics. Psychopharmacology (Berlin) 1987; 92: 14–24.
Laakmann G, Gugath M, Kuss HJ, Zygan k. assessment of growth hormone and prolactin stimulation caused by way of chlorimipramine and desimipramine in man in reference to chlorimipramine metabolism. Psychopharmacology (Berlin) 1984; 82: 62–67.
Golden RN, Ekstrom D, Brown TM, Ruegg R, Evans DL, Haggerty Jr JJ et al. Neuroendocrine effects of intravenous clomipramine in depressed sufferers and felicitous subjects. Am J Psychiatry 1992; 149: 1168–1175.
Reist C, Helmeste D, Albers L, Chhay H, Tang SW. Serotonin indices and impulsivity in regular volunteers. Psychiatry Res 1996; 60: 177–184.
Kavoussi RJ, Kramer J, Hauger RL, Coccaro EF. Prolactin response to D-fenfluramine in outpatients with main melancholy. Psychiatry Res 1998; seventy nine: 199–205.
Quattrone A, Tedeschi G, Aguglia U, Scopacasa F, Direnzo GF, Annunziato L. Prolactin secretion in man: a much instrument to evaluate the undertaking of drugs on primary 5-hydroxytryptaminergic neurons. reports with fenfluramine. Br J Clin Pharmacol 1983; 16: 471–475.
Sher L, Oquendo MA, Li S, Ellis S, Brodsky BS, Malone KM et al. Prolactin response to fenfluramine administration in sufferers with unipolar and bipolar depression and robust controls. Psychoneuroendocrinology 2003; 28: 559–573.
Newman ME, Shapira B, Lerer B. comparison of faultfinding serotonergic feature in affective and related issues by the fenfluramine problem verify: a vital review. Int J Neuropsychopharmcol 1998; 1: 49–69.
O'Keane V, McLoughlin D, Dinan TG. D-Fenfluramine-precipitated prolactin and cortisol unencumber in most well-known melancholy: response to remedy. J influence Disord 1992; 26: 143–150.
Shapira B, Cohen J, Newman ME, Lerer B. Prolactin response to fenfluramine and placebo challenge following maintenance pharmacotherapy withdrawal in remitted depressed sufferers. Biol Psychiatry 1993; 33: 531–535.
Kasper S, Vieira A, Schmidt R, Richter P. assorted hormone responses to stimulation with dl-fenfluramine in patients with major depression earlier than and after antidepressive remedy. Pharmacopsychiatry 1990; 23: 76–eighty four.
Seifritz E, Baumann P, Muller MJ, Annen O, Amey M, Hemmeter U et al. Neuroendocrine effects of a 20-mg citalopram infusion in suit males. A placebo-managed assessment of citalopram as 5-HT feature probe. Neuropsychopharmacology 1996; 14: 253–263.
Attenburrow MJ, Mitter PR, Whale R, Terao T, Cowen PJ. Low-dose citalopram as a 5-HT neuroendocrine probe. Psychopharmacology (Berlin) 2001; a hundred and fifty five: 323–326.
Porter RJ, Gallagher P, Watson S, Smith MS, younger AH. increased prolactin responses to L-tryptophan infusion in medicine-free depressed patients. Psychopharmacology (Berlin) 2003; 169: 77–eighty three.
Fernstrom JD. Dietary effects on brain serotonin synthesis: relationship to exhort for food legislation. Am J Clin Nutr 1985; 42: 1072–1082.
Fernstrom JD. aromatic amino acids and monoamine synthesis within the central apprehensive gadget: hold an consequence on of the diet. J Nutr Biochem 1990; 1: 508–517.
Fernstrom JD, Wurtman RJ. brain serotonin content material: enhance following ingestion of carbohydrate eating regimen. Science 1971; 174: 1023–1025.
Markus CR, Olivier B, de Haan EH. Whey protein flush in alpha-lactalbumin raises the ratio of plasma tryptophan to the sum of the other large impartial amino acids and improves cognitive efficiency in stress-inclined topics. Am J Clin Nutr 2002; 75: 1051–1056.
Heine W, Radke M, Wutzke KD, Peters E, Kundt G. Alpha-lactalbumin-enriched low-protein baby formulas: a evaluation to breast milk feeding. Acta Paediatr 1996; 85: 1024–1028.
Kalen P, Strecker RE, Rosengren E, Bjorklund A. Endogenous liberate of neuronal serotonin and 5-hydroxyindoleacetic acid in the caudate-putamen of the rat as revealed by way of intracerebral dialysis coupled to high-performance liquid chromatography with fluorimetric detection. J Neurochem 1988; 51: 1422–1435.
Orosco M, Rouch C, Beslot F, Feurte S, Regnault A, Dauge V. Alpha-lactalbumin-enriched diets boost serotonin liberate and set off anxiolytic and lucrative consequences in the rat. Behav intellect Res 2004; 148: 1–10.
Markus R, Panhuysen G, Tuiten A, Koppeschaar H. outcomes of meals on cortisol and humor in susceptible subjects beneath controllable and uncontrollable stress. Physiol Behav 2000; 70: 333–342.
Markus CR, Olivier B, Panhuysen GE, Van Der Gugten J, Alles MS, Tuiten A et al. The bovine protein alpha-lactalbumin increases the plasma ratio of tryptophan to the different stupendous neutral amino acids, and in prone subjects raises intellect serotonin exercise, reduces cortisol awareness, and improves temper under stress. Am J Clin Nutr 2000; 71: 1536–1544.
Mann JJ, McBride PA, Malone KM, DeMeo M, Keilp J. Blunted serotonergic responsivity in depressed inpatients. Neuropsychopharmacology 1995; 13: 53–64.
Balldin J, Berggren U, Engel J, Eriksson M. Neuroendocrine facts for reduced serotonergic neurotransmission privilege through heavy drinking. Alcohol Clin Exp Res 1994; 18: 822–825.
Whale R, Quested DJ, Laver D, Harrison PJ, Cowen PJ. Serotonin transporter (5-HTT) promoter genotype might likewise impact the prolactin response to clomipramine. Psychopharmacology (Berlin) 2000; one hundred fifty: a hundred and twenty–122.
Smith GS, Lotrich FE, Malhotra AK, Lee AT, Ma Y, Kramer E et al. consequences of serotonin transporter promoter polymorphisms on serotonin characteristic. Neuropsychopharmacology 2004; 29: 2226–2234.
Fernstrom JD, Wurtman RJ. intellect serotonin content material: physiological legislation through plasma impartial amino acids. Science 1972; 178: 414–416.
Lieben CK, Blokland A, Westerink B, Deutz NE. Acute tryptophan and serotonin depletion the utilize of an optimized tryptophan-free protein-carbohydrate blend within the adult rat. Neurochem Int 2004; 44: 9–16.
younger SN, Smith SE, Pihl RO, Ervin FR. Tryptophan depletion reasons a speedy reducing of humor in commonplace men. Psychopharmacology (Berlin) 1985; 87: 173–177.
Stancampiano R, Melis F, Sarais L, Cocco S, Cugusi C, Fadda F. Acute administration of a tryptophan-free amino acid amalgam decreases 5-HT unencumber in rat hippocampus in vivo. Am J Physiol 1997; 272: R991–R994.
Biggio G, Fadda F, Fanni P, Tagliamonte A, Gessa GL. swift depletion of serum tryptophan, intellect tryptophan, serotonin and 5-hydroxyindoleacetic acid by means of a tryptophan-free diet. lifestyles Sci 1974; 14: 1321–1329.
Moja EA, Cipolla P, Castoldi D, Tofanetti O. Dose-response decrease in plasma tryptophan and in brain tryptophan and serotonin after tryptophan-free amino acid mixtures in rats. lifestyles Sci 1989; 44: 971–976.
Bel N, Artigas F. reduction of serotonergic duty in rat brain through tryptophan depletion: effects in handle and fluvoxamine-treated rats. J Neurochem 1996; 67: 669–676.
wood worker LL, Anderson GM, Pelton GH, Gudin JA, Kirwin PD, fee LH et al. Tryptophan depletion every bit of the way through continuous CSF sampling in in shape human subjects. Neuropsychopharmacology 1998; 19: 26–35.
Williams WA, Shoaf SE, Hommer D, Rawlings R, Linnoila M. outcomes of acute tryptophan depletion on plasma and cerebrospinal fluid tryptophan and 5-hydroxyindoleacetic acid in customary volunteers. J Neurochem 1999; seventy two: 1641–1647.
Blokland A, Lieben C, Deutz NE. Anxiogenic and depressive-like effects, however no cognitive deficits, after repeated reasonable tryptophan depletion within the rat. J Psychopharmacol 2002; 16: 39–forty nine.
Delgado PL, rate LH, Miller HL, Salomon RM, Aghajanian GK, Heninger GR et al. Serotonin and the neurobiology of depression. outcomes of tryptophan depletion in drug-free depressed patients. Arch Gen Psychiatry 1994; fifty one: 865–874.
Van der Does AJ. The outcomes of tryptophan depletion on temper and psychiatric signs. J hold an consequence on Disord 2001; 64: 107–119.
Ellenbogen MA, green SN, Dean P, Palmour RM, Benkelfat C. humor response to acute tryptophan depletion in suit volunteers: sex ameliorations and temporal steadiness. Neuropsychopharmacology 1996; 15: 465–474.
Smith KA, Fairburn CG, Cowen PJ. Relapse of depression after quickly depletion of tryptophan. Lancet 1997; 349: 915–919.
Benkelfat C, Ellenbogen MA, Dean P, Palmour RM, younger SN. temper-lowering consequence of tryptophan depletion. improved susceptibility in green men at genetic risk for foremost affective problems. Arch Gen Psychiatry 1994; 51: 687–697.
Taffe MA, Huitron-Resendiz S, Schroeder R, Parsons LH, Henriksen SJ, Gold LH. MDMA publicity alters cognitive and electrophysiological sensitivity to speedy tryptophan depletion in rhesus monkeys. Pharmacol Biochem Behav 2003; 76: 141–152.
Van der Does AJ. The mood-lowering consequence of tryptophan depletion: feasible understanding for discrepant findings. Arch Gen Psychiatry 2001; 58: 200–202.
Spillmann MK, Van der Does AJ, Rankin MA, Vuolo RD, Alpert JE, Nierenberg AA et al. Tryptophan depletion in SSRI-recovered depressed outpatients. Psychopharmacology (Berlin) 2001; a hundred and fifty five: 123–127.
Booij L, Van der Does AJ, Haffmans PM, Riedel WJ, Fekkes D, Blom MJ. The outcomes of excessive-dose and low-dose tryptophan depletion on temper and cognitive functions of remitted depressed sufferers. J Psychopharmacol 2005; 19: 267–275.
Booij L, van der Does AJ, Haffmans PM, Spinhoven P, McNally RJ. Acute tryptophan depletion as a model of depressive relapse: behavioural specificity and ethical concerns. Br J Psychiatry 2005; 187: 148–154.
Leentjens AF, Scholtissen B, Vreeling FW, Verhey FR. The serotonergic speculation for melancholy in Parkinson's disorder: an experimental method. Neuropsychopharmacology 2006; 31: 1009–1015.
EDMONTON, Jan. 24, 2012 /CNW/ - Canadian Western bank (TSX: CWB) these days launched its 2011 quarterly and annual financial consequences as suggested beneath international economic Reporting requirements (IFRS).
The Canadian Institute of Chartered Accountants has transitioned Canadian generally authorised accounting ideas (GAAP) for publicly in suffuse entities to IFRS. The transition is applicable to meantime and annual financial statements valuable for fiscal years starting on or after January 1, 2011, including comparatives for the prior year. due to this fact, Canadian Western bank's (CWB or the financial institution) consolidated fiscal statements for the 2012 fiscal year could exist organized in accordance with IFRS, together with comparative suggestions for 2011. CWB's economic effects for the quarter ending January 31, 2012 might exist the first quarterly IFRS economic statements and are expected to exist released before the market opens on March 8, 2012.
right here assistance, besides the bank's prior disclosure, is provided to advocate users of the monetary statements more suitable exist mindful the hold an impact on on CWB's 2011 consolidated fiscal statements because of the initial adoption of IFRS. This guidance may quiet exist examine together with the long Run changes in Accounting policies component to the management's discussion and evaluation (MD&A) within CWB's 2011 Annual report, purchasable on SEDAR at www.sedar.com and the financial institution's web page at www.cwbankgroup.com.
it is crucial to recognize that the transition to IFRS is an accounting trade best and doesn't mirror a change within the underlying companies or strategy of CWB.
impact on Key performance Metrics
A summary of CWB's key efficiency metrics for fiscal 2011 as stated under Canadian GAAP and restated for IFRS follows:($ heaps) Canadian GAAP IFRS(unaudited) internet income obtainable to regular shareholders $162,941 $149,538 complete revenue (teb) (1) $491,014 $483,555 total loans $12,221,143 $12,293,282 internet hobby margin (teb) (2) 2.eighty two% 2.ninety nine% Provision for credit losses as a percentage ofaverage loans 20 foundation facets 19 foundation facets efficiency ratio (teb) forty five.three% forty four.9% Return on regular shareholders' equity 15.6% 14.7% Return on assets 1.20% 1.09% Diluted earnings per general share $2.12 $1.ninety five Diluted money earnings per typical participate (3) $2.18 $2.17 (1) teb - search counsel from the "Taxable equal foundation (teb)" ingredient of this tidings liberate for definition. (2) The enhance in web hobby margin reflects a non-IFRS trade in consciousness of distinct credit score related charges as described within the "colossal Accounting policy transformations" ingredient of this information free up. (3) Diluted cash revenue per participate is diluted salary per customary participate aside from the after-tax amortization of acquisition-related intangible assets and the non-tax deductible trade in reasonable charge of the contingent consideration related to the countrywide Leasing acquisition.
As described in the 2011 annual MD&A, probably the most vast alterations relate to:
IFRS income changes
A summary of the adjustments in 2011 web revenue attainable to standard shareholders on account of the adoption of IFRS follows:($ heaps, unaudited) Q1 2011 Q2 2011 Q3 2011 this topple 2011 Fiscal 2011 web earnings attainable to standard shareholders under $ forty,150 $ forty,638 $ forty,909 $ forty one,244 $ 162,941 Canadian GAAP IFRS adjustments: business combinations (country wide Leasing) (2,516) (three,742) (2,508) (three,539) (12,305) Derecognition of securitized rentals218 forty five 423 423 1,109 attainable-for-sale securities impairment - - - (2,207) (2,207) internet revenue available to common shareholders beneath $ 37,852 $ 36,941 $ 38,824 $ 35,921 $ 149,538 IFRS
big Accounting policy differences
enormous accounting coverage adjustments for the bank on preliminary transition to IFRS and any elections made are described beneath with every bit of transformations regarding the Banking and believe working phase.
(1) business combinations - below IFRS, contingent consideration concerning a company combination is accounted for as a financial legal responsibility and reasonable valued at the time of the acquisition. An adjustment of the liability to latest reasonable cost is recorded via web income each length thereafter except settlement. beneath Canadian GAAP, when the quantity of contingent consideration can't exist moderately estimated or the consequence of the contingency can not exist determined without not pricey doubt, the liability isn't recognized unless the contingency is resolved and consideration is issued or becomes issuable; at such time, the consideration is recorded as an adjustment of goodwill.
The financial institution has applied IFRS three - business combos retrospectively to the national Leasing acquisition (described in note 34 to the 2011 annual consolidated fiscal statements on page 119 of the 2011 Annual report). under IFRS 1: First Time Adoption of IFRS, the associated contingent consideration turned into reasonable valued on the acquisition date of February 1, 2010.
The retrospective restatement expanded IFRS goodwill recorded on the consolidated stability sheet at November 1, 2010 by $eight million. The revaluation of the contingent consideration considering that acquisition diminished retained salary at November 1, 2010 via $10 million. The net consequence of revaluing the responsibility in fiscal 2011 resulted in a $12 million reduction in net salary.
The change in just value of the contingent consideration reflects the financial institution's top of the line rate of when the contingent consideration will exist settled, based on the terms of the buy shrink and estimates of countrywide Leasing's future revenue. increases within the estimated reasonable value of the contingent consideration outcomes in a non-tax deductible can suffuse to quarterly income according to forecasted income growth attributable to national Leasing, changes in administration's estimates of the anticipated agreement of the contingent consideration and a notional activity can charge. Future prices to quarterly profits as a result of the just value rate of the contingent consideration are anticipated to exist lessen compared to amounts reported in 2011, as 2011 prices included a bigger adjustment to forecasted internet profits than is anticipated going forward.
(2) Derecognition of Securitized fiscal property - country wide Leasing's securitized leases are stated as loans on the IFRS equilibrium sheet and resulted in an increase in each loans and debt. The corresponding impact on net revenue in fiscal 2011 become insignificant. The IFRS transition resulted in privilege here raise in complete loans at the respective steadiness sheet dates:($ hundreds of thousands, unaudited) enhance in total loans November 1, 2010 $ 196 January 31, 2011 167 April 30, 2011 one hundred forty July 31, 2011 114 October 31, 2011 ninety
The earnings impact of securitization as pronounced beneath IFRS resulted in a $2 million lower in retained income as at November 1, 2010. The change displays the elimination of cumulative securitization features and losses realized under Canadian GAAP, much less cognizance of interest revenue and expense below IFRS. The internet consequence on 2011 consolidated net income become a ascend of $1 million.
the future earnings hold an consequence on from securitization transactions completed in promote of October 31, 2011 is anticipated to exist insignificant. Leases securitized sooner or later will continue to exist on the consolidated steadiness sheet said as loans.
(three) Consolidation - beneath IFRS, a variable activity entity (VIE) is consolidated if it is deemed to exist managed via the reporting entity, as determined under specific criteria. Canadian Western financial institution Capital believe is consolidated beneath IFRS, which resulted in a $a hundred and five million lessen in deposits and the presentation of the CWB Capital believe Capital Securities collection 1 (WesTS) as fairness attributed to non-controlling interests. Distributions on the WesTS that had been with no disaster mentioned as deposit hobby expense at the minute are introduced as an equity dividend within IFRS "web revenue caused by non-controlling interests." For greater suggestions about this special purpose entity, search counsel from notice 15 to the consolidated economic statements genesis on web page a hundred of the 2011 Annual document.
The web consequence on 2011 consolidated "web income" without problems resulted in an increase of $7 million because the deposit interest cost below Canadian GAAP is treated as an fairness dividend payment below IFRS. "web earnings because of shareholders of the financial institution" is stated net of the non-controlling hobby and remains unchanged for 2011.
(four) Impairment of available-for-Sale Securities - beneath both Canadian GAAP and IFRS, obtainable-for-sale securities are stated on the steadiness sheet at just value with changes in just value commonly mentioned in other finished income. An unrealized loss is identified in internet income when a security is considered impaired; a subsequent recuperation within the cost of an fairness safety isn't reversed via web salary except the security is both offered or redeemed. beneath Canadian GAAP, a significant or extended decline in the just value of an investment under its suffuse is classified within the context of whether it is regarded an "other than temporary impairment" (OTTI). beneath IFRS, the conception of OTTI doesn't exist and both a significant or prolonged decline in reasonable value is considered objective proof of impairment. The differences between Canadian GAAP and IFRS will often outcomes in earlier attention of impairment losses through net earnings under IFRS.
The influence of the transition effects in no change in shareholders' fairness and a $2 million discount in 2011 web income. The impact of the IFRS definition of large or prolonged impairment on the bank's future income isn't determinable as it is conditional upon the long Run interest expense atmosphere, market circumstances, funding ideas and the financial institution's asset/legal responsibility position.
(5) other Reclassifications - distinct other financial plot reclassifications were made on the transition to IFRS. An instance contains the presentation of the non-controlling interest in Adroit funding management Ltd. which has been reclassified from different liabilities under Canadian GAAP to non-controlling interests (introduced in equity) beneath IFRS.
moreover the IFRS transition adjustments previously described, the awareness of inevitable credit related costs changed into additionally amended. inevitable credit linked costs, up to now recognized in different profits, are now considered a portion of the mortgage yield and amortized to web activity earnings over the expected life of the loan. as a result of complete loans are pronounced internet of deferred mortgage fees, this change resulted in a reduce in total loans of $18 million at each November 1, 2010 and October 31, 2011, and a discount in retained revenue of $13 million at November 1, 2010. while the exchange had no hold an consequence on on 2011 internet earnings, approximately $15 million changed into reclassified from different profits to net activity profits leading to a 17 groundwork factor increase within the fiscal 2011 IFRS web pastime margin (teb) compared to Canadian GAAP. The hold an consequence on on the earnings commentary in future intervals is anticipated to exist relatively consistent with 2011.
precise 2011 financial outcomes reconciled from Canadian GAAP to IFRS are blanketed in the following appendices:
CWB's October 31, 2011 supplemental fiscal information kit organized beneath IFRS is accessible on the bank's web site at www.cwbankgroup.com. The unaudited fiscal statements for the quarter ending January 31, 2012 will include an entire summary of every bit of huge IFRS accounting guidelines.
anticipated Regulatory Capital Implications
As at October 31, 2011, the professional forma Basel II Tier 1 and complete regulatory capital ratios hold been estimated to decline 40 groundwork features below IFRS to 10.7% and 15.0%, respectively. After due to the fact IFRS transition changes, these ratios continue to exist smartly above each regulatory minimums and goal capital thresholds decided through the bank's inside Capital Adequacy assessment system (ICAAP).
under IFRS, leases securitized and offered by means of country wide Leasing are accounted for as secured borrowings. consciousness of securitized belongings on the consolidated steadiness sheet raises the regulatory asset-to-capital diverse. As at October 31, 2011, the pro-forma asset-to-capital dissimilar, together with IFRS transition adjustments, turned into estimated to boost to eight.1, from 7.9, and is quiet well in the regulatory restrict.
Fiscal 2012 minimal performance goals
The bank's minimum efficiency ambitions conditional for fiscal 2012 as offered in the 2011 Annual record hold been calculated below Canadian GAAP. With the restatement of 2011 results from Canadian GAAP to IFRS, the 2012 performance targets were adjusted to reflect the IFRS transition on the underlying monetary statistics. management's assumptions regarding the company outlook for 2012 remain consistent with the discussion within the 2011 Annual record.2012 MinimumPerformance goals-- Canadian GAAP 2012 MinimumPerformance objectives-- IFRS internet salary obtainable to commonplace shareholders boom (1) 6% 10% complete revenues (teb) growth 6% 7% total mortgage boom 10% 10% Provision for credit losses as a percentage of common loans 0.20% - 0.25% 0.20% - 0.25% effectivity ratio (teb) (2) forty six% forty six% Return on standard shareholders' fairness (three) 15% 15% Return on belongings (4) 1.10% 1.05% (1) web income because of regular shareholders of the bank after favored participate dividends. (2) efficiency ratio (teb) calculated as non-pastime fees divided by total revenues (teb), apart from thechange in just charge influence of the contingent consideration involving the acquisition of national Leasing. (3) Return on ordinary shareholders' equity calculated as web earnings because of commonplace shareholders ofthe bank after favourite participate dividends divided by standard typical shareholders' fairness. (4) Return on assets calculated as annualized web revenue as a result of middling shareholders of the Bankafter favorite participate dividends divided by regular total belongings
Taxable equal foundation (teb)
Most banks dissect salary on a taxable equivalent basis to let uniform size and comparison of internet interest income. web hobby salary (as introduced in the consolidated remark of salary) includes tax-exempt salary on inevitable securities. because this revenue is not taxable, the cost of activity or dividends obtained is greatly reduce than would apply to a personal loan or protection of the equal amount. The adjustment to taxable equal groundwork increases interest salary and the provision for revenue taxes to what they'd were had the tax-exempt securities been taxed at the statutory fee. The taxable equal groundwork does not hold a standardized which means prescribed via GAAP or IFRS and, for this reason, can likewise no longer exist comparable to identical measures offered with the aid of other banks. total revenues, net pastime salary and revenue taxes are mentioned on a taxable equal basis throughout this press unencumber.
Taxable equivalent foundation, revert on typical shareholders' fairness, revert on assets, effectivity ratio, internet hobby margin, Tier 1 and total capital adequacy ratios, general balances and provision for credit score losses as a percent of general loans would not hold standardized meanings prescribed by Canadian GAAP or IFRS and, hence, may additionally not exist similar to an identical measures offered by other fiscal associations. The non-GAAP measures used in this press unencumber are calculated as follows:
now and again, Canadian Western financial institution (the financial institution) makes written and verbal ahead-looking statements. Statements of this kind are protected within the Annual record and experiences to shareholders and can exist covered in filings with Canadian securities regulators or in different communications reminiscent of press releases and corporate displays. forward-looking statements encompass, but are not constrained to, statements in regards to the financial institution's pursuits and techniques, targeted and expected financial results and the outlook for the financial institution's businesses or for the Canadian economy. ahead-looking statements are customarily identified through the words "believe", "predict", "count on", "intend", "estimate", "can likewise enhance", "can likewise hold an impact on" and different similar expressions, or future or conditional verbs comparable to "will", "should still", "would" and "might."
through their very nature, ahead-searching statements accommodate numerous assumptions. loads of elements, many of which are past the financial institution's manage, could antecedent exact outcomes to vary materially from the expectations expressed within the forward-searching statements. These components consist of, however are not restrained to, time-honored company and economic situations in Canada together with the volatility and shortage of liquidity in monetary markets, fluctuations in activity charges and forex values, changes in fiscal coverage, adjustments in financial and political conditions, regulatory and felony tendencies, the level of competitors in the bank's markets, the prevalence of weather-connected and other natural catastrophes, adjustments in accounting requisites and guidelines, the accuracy of and completeness of information the bank receives about valued clientele and counterparties, the skill to attract and maintain key personnel, the skill to comprehensive and combine acquisitions, reliance on third parties to give add-ons of the financial institution's enterprise infrastructure, alterations in tax laws, technological developments, sudden alterations in customer spending and saving habits, well timed evolution and introduction of recent products, and management's capability to anticipate and manage the dangers linked to these factors. it is well-known to note that the previous listing isn't exhaustive of viable elements.
These and other elements may quiet exist considered carefully and readers are counseled no longer to dwelling undue reliance on these ahead-searching statements as a few vital factors may trigger the bank's genuine effects to disagree materially from the expectations expressed in such ahead looking statements. until required through securities legislations, the bank doesn't undertake to replace any forward-looking observation, no matter if written or verbal, that may exist made from time to time by using it or on its behalf.
Assumptions in regards to the performance of the Canadian economic system in 2012 and how it will hold an consequence on CWB's businesses are material factors the financial institution considers when surroundings its targets. In atmosphere minimal performance aims for fiscal 2012, administration's assumptions covered: modest economic increase in Canada aided with the aid of fine relative efficiency within the four western provinces; extraordinarily solid energy and different commodity fees; sound credit score character with actual losses final inside the bank's dilapidated latitude of flawless ranges; and, a reduce internet hobby margin attributed to expectations for a protracted epoch of very low pastime prices due to uncertainties about the power of international economic recuperation and capabilities antagonistic results from the european debt disaster.
About Canadian Western bank neighborhood
Canadian Western bank offers a plenary compass of company and private banking services throughout the 4 western provinces and is the greatest publicly traded Canadian financial institution headquartered in Western Canada. The financial institution, along with its operating associates, country wide Leasing neighborhood Inc., Canadian Western confidence company, Valiant confidence enterprise, Canadian Direct assurance integrated, Adroit investment management Ltd. and Canadian Western monetary Ltd., jointly present a various latitude of financial features across Canada and are together everyday because the Canadian Western financial institution community. The middling shares of Canadian Western bank are listed on the Toronto stock exchange beneath the trading image "CWB". The financial institution's sequence three preferred Shares alternate on the Toronto inventory change below the buying and selling emblem "CWB.PR.A". search counsel from www.cwbankgroup.com for additional information.
Appendix AReconciliation of Condensed Consolidated steadiness Sheet As at November 1, 2010 (Unaudited) ($ thousands) IFRS alterations (1) (2) (3) (four) Canadian enterprise AFS GAAP combinations Derecognition Consolidation Impairment other IFRS property cash supplies, securities and securities beneath resale agreements $ 1,876,085 $ - $ - $ - $ - $ - $ 1,876,085 Loans 10,496,464 - 196,215 - - (17,982) 10,674,697 other assets 329,142 7,839 (10,567) - - 4,532 330,946 complete property $ 12,701,691 $ 7,839 $ 185,648 $ - $ - $ (13,450) $ 12,881,728 Liabilities Deposits $ 10,812,767 $ - $ - $ (a hundred and five,000) $ - $ - $ 10,707,767 other liabilities 425,881 17,835 (14,047) - - (179) 429,490 Debt 315,000 - 202,006 - - - 517,006 total liabilities 11,553,648 17,835 187,959 (a hundred and five,000) - (179) 11,654,263 Shareholders' equity 1,148,043 (9,996) (2,311) - - (13,450) 1,122,286 Non-controlling activity - - - one zero five,000 - 179 one hundred and five,179 complete equity 1,148,043 (9,996) (2,311) one zero five,000 - (13,271) 1,227,465 total liabilities and fairness $ 12,701,691 $ 7,839 $ 185,648 $ - $ - $ (13,450) $ 12,881,728
Appendix BReconciliation of Condensed Consolidated income Statements For the three months ended January 31, 2011 (Unaudited) ($ hundreds) IFRS changes (1) (2) (3) (four) Canadian business AFS GAAP combinations Derecognition Consolidation Impairment other IFRS internet hobby salary (teb) (1) $ ninety three,426 $ - $ 1,804 $ 1,700 $ - $ four,287 $ one hundred and one,217 Provision for credit losses 6,216 - 34 - - - 6,250 other income 28,421 (2,516) (1,472) - - (4,287) 20,146 Non-activity expenses 55,128 - - - - - fifty five,128 profits taxes (teb) sixteen,491 - eighty - - - sixteen,571 Non-controlling pastime in subsidiary 60 - - - - (60) - internet salary forty three,952 (2,516) 218 1,700 - 60 forty three,414 net earnings brought on by non-controlling hobbies - - - 1,seven-hundred - 60 1,760 internet profits brought on by shareholders of the bank $ 43,952 $ (2,516) $ 218 $ - $ - $ - $ 41,654 favorite participate dividends three,802 - - - - - 3,802 net revenue available to commonplace shareholders $ 40,a hundred and fifty $ (2,516) $ 218 $ - $ - $ - $ 37,852 For the three months ended April 30, 2011 (Unaudited) ($ lots) IFRS adjustments (1) (2) (three) (4) Canadian business AFS GAAP mixtures Derecognition Consolidation Impairment different IFRS web activity earnings (teb) $ ninety three,282 $ - $ 1,337 $ 1,647 $ - $ 2,899 $ ninety nine,165 Provision for credit losses 5,267 - eleven - - - 5,278 different profits 28,506 (three,742) (1,264) - - (2,899) 20,601 Non-pastime fees 55,408 - - - - - 55,408 earnings taxes (teb) 16,623 - 17 - - - 16,640 Non-controlling interest in subsidiary 50 - - - - (50) - net revenue forty four,440 (3,742) forty five 1,647 - 50 42,440 internet income as a result of non-controlling pastimes - - - 1,647 - 50 1,697 internet profits caused by shareholders of the financial institution $ 44,440 $ (three,742) $ forty five $ - $ - $ - $ 40,743 favored participate dividends 3,802 - - - - - three,802 web income accessible to regular shareholders $ forty,638 $ (three,742) $ 45 $ - $ - $ - $ 36,941 (1) search counsel from the "Non-GAAP Measures" portion of this information unencumber for a definition of teb (taxable equivalent basis)
For the three months ended July 31, 2011 (Unaudited) ($ lots) IFRS changes (1) (2) (three) (4) Canadian enterprise AFS GAAP mixtures Derecognition Consolidation Impairment different IFRS internet interest earnings (teb) (1) $ 98,133 $ - $ 1,361 $ 1,seven hundred $ - $ 3,692 $ 104,886 Provision for credit score losses 5,one hundred seventy five - (103) - - - 5,072 different salary 24,952 (2,508) (885) - - (three,692) 17,867 Non-interest prices 55,805 - - - - - fifty five,805 revenue taxes (teb) 17,327 - 156 - - - 17,483 Non-controlling pastime in subsidiary 67 - - - - (sixty seven) - net salary forty four,711 (2,508) 423 1,700 - 67 forty four,393 net earnings as a result of non-controlling interests - - - 1,seven hundred - 67 1,767 net profits as a result of shareholders of the bank $ 44,711 $ (2,508) $ 423 $ - $ - $ - $ forty two,626 preferred participate dividends three,802 - - - - - three,802 internet revenue available to common shareholders $ forty,909 $ (2,508) $ 423 $ - $ - $ - $ 38,824 For the three months ended October 31, 2011 (Unaudited) ($ hundreds) IFRS changes (1) (2) (3) (four) Canadian business AFS GAAP combos Derecognition Consolidation Impairment other IFRS web activity salary (teb) $ ninety nine,842 $ - $ 1,006 $ 1,seven-hundred $ - $ 3,636 $ 106,184 Provision for credit score losses 5,521 - (338) - - - 5,183 different salary 24,452 (three,539) (765) - (three,023) (3,636) 13,489 Non-activity charges 56,110 - - - - - fifty six,a hundred and ten earnings taxes (teb) 17,566 - 156 - (816) - sixteen,906 Non-controlling hobby in subsidiary 51 - - - - (51) - web salary 45,046 (3,539) 423 1,700 (2,207) fifty one 41,474 net revenue brought on by non-controlling pastimes - - - 1,seven hundred - fifty one 1,751 web revenue caused by shareholders of the bank $ forty five,046 $ (3,539) $ 423 $ - $ (2,207) $ - $ 39,723 favourite participate dividends 3,802 - - - - - 3,802 internet salary purchasable to standard shareholders $ 41,244 $ (three,539) $ 423 $ - $ (2,207) $ - $ 35,921 (1) search counsel from the "Non-GAAP Measures" ingredient of this tidings unencumber for a definition of teb (taxable equivalent groundwork)
Appendix CReconciliation of Condensed Consolidated stability Sheet As at October 31, 2011 (Unaudited) ($ thousands) IFRS changes (1) (2) (three) (four) Canadian company AFS GAAP combinations Derecognition Consolidation Impairment different IFRS assets cash components, securities and securities under resale agreements $ 2,238,039 $ - $ - $ - $ - $ - $ 2,238,039 Loans 12,221,143 - ninety,121 - - (17,982) 12,293,282 different property 312,853 7,839 (7,404) - - 4,532 317,820 complete belongings $ 14,772,035 $ 7,839 $ 82,717 $ - $ - $ (13,450) $ 14,849,141 Liabilities Deposits $ 12,499,689 $ - $ - $ (a hundred and five,000) $ - $ - $ 12,394,689 other liabilities 433,780 30,140 (5,958) - - (225) 457,737 Debt 545,000 - 89,877 - - - 634,877 total liabilities 13,478,469 30,a hundred and forty eighty three,919 (105,000) - (225) 13,487,303 Shareholders' fairness 1,293,566 (22,301) (1,202) - - (13,450) 1,256,613 Non-controlling pursuits - - - one zero five,000 - 225 one zero five,225 total fairness 1,293,566 (22,301) (1,202) one hundred and five,000 - (13,225) 1,361,838 total liabilities and fairness $ 14,772,035 $ 7,839 $ eighty two,717 $ - $ - $ (13,450) $ 14,849,141 Reconciliation of Condensed Consolidated earnings commentary For the yr ended October 31, 2011 (Unaudited) ($ hundreds) IFRS adjustments (1) (2) (3) (four) Canadian enterprise AFS GAAP combos Derecognition Consolidation Impairment other IFRS web hobby earnings (teb) (1) $ 384,683 $ - $ 5,508 $ 6,747 $ - $ 14,514 $ 411,452 Provision for credit losses 22,179 - (396) - - - 21,783 other earnings 106,331 (12,305) (4,386) - (three,023) (14,514) 72,103 Non-interest charges 222,451 - - - - - 222,451 income taxes (teb) sixty eight,007 - 409 - (816) - 67,600Non-controlling pastime in subsidiary 228 - - - - (228) - net income 178,149 (12,305) 1,109 6,747 (2,207) 228 171,721 internet salary attributable to non-controlling pastimes - - - 6,747 - 228 6,975 net earnings caused by shareholders of the financial institution $ 178,149 $ (12,305) $ 1,109 $ - $ (2,207) $ - $ 164,746 favorite participate dividends 15,208 - - - - - 15,208 web income attainable to commonplace shareholders $ 162,941 $ (12,305) $ 1,109 $ - $ (2,207) $ - $ 149,538
(1) dispute with the "Non-GAAP Measures" component to this tidings liberate for a definition of teb (taxable equal basis)
supply Canadian Western bank
For extra tips:Tracey C. Ball, FCAExecutive vp and Chief financial OfficerCanadian Western BankPhone: (780) 423-8855 Kirby Hill, CFADirector, Investor and Public RelationsCanadian Western BankPhone: (780) 441-3770Email: firstname.lastname@example.org
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ASTQB [6 Certification Exam(s) ]
Autodesk [2 Certification Exam(s) ]
Avaya [87 Certification Exam(s) ]
Axis [1 Certification Exam(s) ]
Banking [1 Certification Exam(s) ]
BEA [5 Certification Exam(s) ]
BICSI [2 Certification Exam(s) ]
BlackBerry [17 Certification Exam(s) ]
BlueCoat [2 Certification Exam(s) ]
Brocade [4 Certification Exam(s) ]
Business-Objects [11 Certification Exam(s) ]
Business-Tests [4 Certification Exam(s) ]
CA-Technologies [20 Certification Exam(s) ]
Certification-Board [9 Certification Exam(s) ]
Certiport [3 Certification Exam(s) ]
CheckPoint [33 Certification Exam(s) ]
CIPS [4 Certification Exam(s) ]
Cisco [303 Certification Exam(s) ]
Citrix [45 Certification Exam(s) ]
CIW [17 Certification Exam(s) ]
Cloudera [10 Certification Exam(s) ]
Cognos [19 Certification Exam(s) ]
College-Board [2 Certification Exam(s) ]
CompTIA [72 Certification Exam(s) ]
ComputerAssociates [6 Certification Exam(s) ]
CPP-Institute [1 Certification Exam(s) ]
CWNP [13 Certification Exam(s) ]
Dassault [2 Certification Exam(s) ]
DELL [7 Certification Exam(s) ]
DMI [1 Certification Exam(s) ]
ECCouncil [19 Certification Exam(s) ]
ECDL [1 Certification Exam(s) ]
EMC [123 Certification Exam(s) ]
Enterasys [13 Certification Exam(s) ]
Ericsson [5 Certification Exam(s) ]
Esri [2 Certification Exam(s) ]
ExamExpress [15 Certification Exam(s) ]
Exin [39 Certification Exam(s) ]
ExtremeNetworks [3 Certification Exam(s) ]
F5-Networks [19 Certification Exam(s) ]
Filemaker [9 Certification Exam(s) ]
Financial [36 Certification Exam(s) ]
Fortinet [10 Certification Exam(s) ]
Foundry [6 Certification Exam(s) ]
Fujitsu [2 Certification Exam(s) ]
GAQM [7 Certification Exam(s) ]
Genesys [4 Certification Exam(s) ]
GIAC [15 Certification Exam(s) ]
Google [4 Certification Exam(s) ]
GuidanceSoftware [2 Certification Exam(s) ]
H3C [1 Certification Exam(s) ]
HDI [9 Certification Exam(s) ]
Healthcare [3 Certification Exam(s) ]
HIPAA [2 Certification Exam(s) ]
Hitachi [27 Certification Exam(s) ]
Hortonworks [3 Certification Exam(s) ]
Hospitality [2 Certification Exam(s) ]
HP [730 Certification Exam(s) ]
HR [1 Certification Exam(s) ]
HRCI [1 Certification Exam(s) ]
Huawei [20 Certification Exam(s) ]
Hyperion [10 Certification Exam(s) ]
IBM [1500 Certification Exam(s) ]
IBQH [1 Certification Exam(s) ]
ICDL [6 Certification Exam(s) ]
IEEE [1 Certification Exam(s) ]
IELTS [1 Certification Exam(s) ]
IFPUG [1 Certification Exam(s) ]
IIBA [2 Certification Exam(s) ]
IISFA [1 Certification Exam(s) ]
Intel [2 Certification Exam(s) ]
IQN [1 Certification Exam(s) ]
IRS [1 Certification Exam(s) ]
ISA [1 Certification Exam(s) ]
ISACA [4 Certification Exam(s) ]
ISC2 [6 Certification Exam(s) ]
ISEB [24 Certification Exam(s) ]
Isilon [4 Certification Exam(s) ]
ISM [6 Certification Exam(s) ]
iSQI [7 Certification Exam(s) ]
Juniper [58 Certification Exam(s) ]
Legato [5 Certification Exam(s) ]
Liferay [1 Certification Exam(s) ]
Lotus [66 Certification Exam(s) ]
LPI [21 Certification Exam(s) ]
LSI [3 Certification Exam(s) ]
Magento [3 Certification Exam(s) ]
Maintenance [2 Certification Exam(s) ]
McAfee [8 Certification Exam(s) ]
McData [3 Certification Exam(s) ]
Medical [25 Certification Exam(s) ]
Microsoft [346 Certification Exam(s) ]
Mile2 [2 Certification Exam(s) ]
Military [1 Certification Exam(s) ]
Misc [1 Certification Exam(s) ]
Motorola [7 Certification Exam(s) ]
mySQL [4 Certification Exam(s) ]
Network-General [12 Certification Exam(s) ]
NetworkAppliance [36 Certification Exam(s) ]
NI [1 Certification Exam(s) ]
Nokia [2 Certification Exam(s) ]
Nortel [130 Certification Exam(s) ]
Novell [37 Certification Exam(s) ]
OMG [9 Certification Exam(s) ]
Oracle [242 Certification Exam(s) ]
P&C [1 Certification Exam(s) ]
Palo-Alto [3 Certification Exam(s) ]
PARCC [1 Certification Exam(s) ]
PayPal [1 Certification Exam(s) ]
Pegasystems [10 Certification Exam(s) ]
PEOPLECERT [4 Certification Exam(s) ]
PMI [15 Certification Exam(s) ]
Polycom [2 Certification Exam(s) ]
PostgreSQL-CE [1 Certification Exam(s) ]
Prince2 [6 Certification Exam(s) ]
PRMIA [1 Certification Exam(s) ]
PTCB [2 Certification Exam(s) ]
QAI [1 Certification Exam(s) ]
QlikView [1 Certification Exam(s) ]
Quality-Assurance [7 Certification Exam(s) ]
RACC [1 Certification Exam(s) ]
Real-Estate [1 Certification Exam(s) ]
RedHat [8 Certification Exam(s) ]
RES [5 Certification Exam(s) ]
Riverbed [8 Certification Exam(s) ]
RSA [13 Certification Exam(s) ]
Sair [8 Certification Exam(s) ]
Salesforce [4 Certification Exam(s) ]
SANS [1 Certification Exam(s) ]
SAP [98 Certification Exam(s) ]
SASInstitute [15 Certification Exam(s) ]
SAT [1 Certification Exam(s) ]
SCO [9 Certification Exam(s) ]
SCP [6 Certification Exam(s) ]
SDI [3 Certification Exam(s) ]
See-Beyond [1 Certification Exam(s) ]
Siemens [1 Certification Exam(s) ]
Snia [6 Certification Exam(s) ]
SOA [15 Certification Exam(s) ]
Social-Work-Board [1 Certification Exam(s) ]
SUN [63 Certification Exam(s) ]
SUSE [1 Certification Exam(s) ]
Sybase [17 Certification Exam(s) ]
Symantec [133 Certification Exam(s) ]
Teacher-Certification [3 Certification Exam(s) ]
The-Open-Group [8 Certification Exam(s) ]
TIA [3 Certification Exam(s) ]
Tibco [18 Certification Exam(s) ]
Trend [1 Certification Exam(s) ]
TruSecure [1 Certification Exam(s) ]
USMLE [1 Certification Exam(s) ]
VCE [6 Certification Exam(s) ]
Veeam [2 Certification Exam(s) ]
Veritas [27 Certification Exam(s) ]
Vmware [52 Certification Exam(s) ]
Wonderlic [1 Certification Exam(s) ]
Worldatwork [2 Certification Exam(s) ]
XML-Master [3 Certification Exam(s) ]
Zend [6 Certification Exam(s) ]
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